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1400566-23-5

4-(4-Fluorophenyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-7-carbonitrile synthesis

1synthesis methods
64248-62-0 Synthesis
3,4-Difluorobenzonitrile

64248-62-0
419 suppliers
$6.00/5g

70453-50-8 Synthesis
N1-(4-Fluorophenyl)-2-mercaptoacetamide

70453-50-8
20 suppliers
$105.00/250mg

4-(4-Fluorophenyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-7-carbonitrile

1400566-23-5
5 suppliers
inquiry

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Yield:1400566-23-5 52%

Reaction Conditions:

with caesium carbonate in N,N-dimethyl-formamide at 80; for 4 h;Inert atmosphere;Smiles Aromatic Rearrangement;

References:

Zhao, Yongmei;Wu, Yanmiao;Jia, Jiong;Zhang, Dongju;Ma, Chen [Journal of Organic Chemistry,2012,vol. 77,# 19,p. 8501 - 8506]