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ChemicalBook CAS DataBase List (6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole
1585969-16-9

(6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole synthesis

8synthesis methods
1585969-17-0 Synthesis
Phenol, 5-bromo-2-[(2R)-5-bromo-2,3-dihydro-1H-indol-2-yl]-

1585969-17-0
20 suppliers
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(6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole

1585969-16-9
10 suppliers
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Yield:1585969-16-9 93%

Reaction Conditions:

with trifluoroacetic acid in acetonitrile at 30 - 35; for 3 h;Inert atmosphere;diastereoselective reaction;

References:

Mangion, Ian K.;Chen, Cheng-Yi;Li, Hongmei;Maligres, Peter;Chen, Yonggang;Christensen, Melodie;Cohen, Ryan;Jeon, Ingyu;Klapars, Artis;Krska, Shane;Nguyen, Hoa;Reamer, Robert A.;Sherry, Benjamin D.;Zavialov, Ilia [Organic Letters,2014,vol. 16,# 9,p. 2310 - 2313] Location in patent:supporting information

1585969-22-7 Synthesis
Phenol, 5-bromo-2-[2-(2,5-dibromophenyl)-1-iminoethyl]-

1585969-22-7
11 suppliers
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(6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole

1585969-16-9
10 suppliers
inquiry

1585969-24-9 Synthesis
(R)-2-(1-amino-2-(2,5-dibromophenyl)ethyl)-5-bromopheno

1585969-24-9
14 suppliers
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(6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole

1585969-16-9
10 suppliers
inquiry