2-(2-fluorophenoxy)benzaldehyde synthesis
- Product Name:2-(2-fluorophenoxy)benzaldehyde
- CAS Number:82097-82-3
- Molecular formula:C13H9FO2
- Molecular Weight:216.21
367-12-4
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446-52-6
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82097-82-3
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Yield:82097-82-3 82%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 100;
Steps:
7 Preparation Example 7: A compound represented by Formula (I-8) was prepared according to Reaction Formula 4, and the substituents were as shown in Table 2, respectively.
General procedure: In a 100 mL round bottom flask, 4 mmol substituted 2-fluorobenzaldehyde represented by Formula I-6 was added, 6 mmol shown in Formula I-2 Substituted phenol and 8 mmol of anhydrous potassium carbonate, After adding 10 mL of DMF, the temperature was raised to 100°C. After TLC monitored the reaction of the raw materials, the reaction was stopped. After adding 50 mL of diethyl ether, the mixture was washed twice with 30 mL of 2 M NaOH and then with 50 mL of saturated brine, and the solvent was evaporated under reduced pressure to give the compound of formula I-8. The rate is shown in Table 2.
References:
CN108069915,2018,A Location in patent:Paragraph 0204-0207
![[2-(2-fluorophenoxy)phenyl]methanol](/CAS/20140525/GIF/CB31593847.gif)
81890-62-2
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82097-82-3
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321-28-8
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82097-82-3
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367-12-4
400 suppliers
$5.00/10g
82097-82-3
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$65.00/100mg
2795-61-1
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82097-82-3
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