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ChemicalBook CAS DataBase List 2,5-Difluoropyridine
84476-99-3

2,5-Difluoropyridine synthesis

9synthesis methods
Taking 2,5-dichloropyridine as raw material, 2,5-dibromopyridine is obtained by halogenation method, and then further through methylation, we can get the product 2,5-difluoropyridine we want. The purity of this crude product can meet the general needs of
2875-18-5 Synthesis
2,3,5,6-Tetrafluoropyridine

2875-18-5
275 suppliers
$12.00/1g

71902-33-5 Synthesis
3,5-Difluoropyridine

71902-33-5
174 suppliers
$6.00/1g

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: C64H68N2OP2Ru; triethylsilane; α,α,α-trifluorotoluene / tetrahydrofuran / 28 h / 69.84 °C / Schlenk technique; Glovebox
2: C64H68N2OP2Ru; triethylsilane; α,α,α-trifluorotoluene / tetrahydrofuran / 28 h / 69.84 °C / Schlenk technique; Glovebox

References:

McKay, David;Riddlestone, Ian M.;Macgregor, Stuart A.;Mahon, Mary F.;Whittlesey, Michael K. [ACS Catalysis,2015,vol. 5,# 2,p. 776 - 787]

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