3-tert-Butylphenol synthesis
- Product Name:3-tert-Butylphenol
- CAS Number:585-34-2
- Molecular formula:C10H14O
- Molecular Weight:150.22
507-20-0
384 suppliers
$13.00/25mL
108-95-2
766 suppliers
$14.00/25g
98-54-4
428 suppliers
$15.00/25g
585-34-2
222 suppliers
$11.00/5g
Yield:-
Reaction Conditions:
with sulfuric acid at 150; for 3 h;Green chemistry;
Steps:
1.1-3.1 Example 1
(1) 10g of phenol,0.1g white clay andAdd 50mg of sulfuric acid to the round bottom reaction bottle, control the reaction temperature at 150 , add 15ml of tert-butyl chloride dropwise, drop the mixture and stir for 3 hours. After the reaction is completed, filter the catalyst and pour the reaction solution into 100ml of water To obtain an organic phase layer and an inorganic phase layer, adding 300 ml of ethyl acetate and extracting three times, combining to obtain an organic phase layer solution, the organic phase layer solution was dried over anhydrous NaSO4, ethyl acetate was recovered, and distilled under reduced pressure,Collect 125 130 / 20mmHg fractions to obtain m-tert-butylphenol with a purity of 98.0%,
References:
China Pharmaceutical University;Huang Dechun;Zhou Yahan;Zhao Bingbing;Chen Jiaxin;Chen Wei CN110903171, 2020, A Location in patent:Paragraph 0023-0024; 0027-0028; 0030-0031
5369-19-7
173 suppliers
$9.00/1g
585-34-2
222 suppliers
$11.00/5g
98-54-4
428 suppliers
$15.00/25g
585-34-2
222 suppliers
$11.00/5g
