1-Methyl-4-[2-nitro-4-(trifluoromethyl)phenyl]piperazine synthesis
1synthesis methods
- Product Name:1-Methyl-4-[2-nitro-4-(trifluoromethyl)phenyl]piperazine
- CAS Number:315239-67-9
- Molecular formula:C12H14F3N3O2
- Molecular Weight:289.25
Yield:-
Reaction Conditions:
with sodium hydrogencarbonate in tetrahydrofuran at 70; for 14 h;
References:
Cee, Victor J.;Albrecht, Brian K.;Geuns-Meyer, Stephanie;Hughes, Paul;Bellon, Steve;Bready, James;Caenepeel, Sean;Chaffee, Stuart C.;Coxon, Angela;Emery, Maurice;Fretland, Jenne;Gallant, Paul;Gu, Yan;Hodous, Brian L.;Hoffman, Doug;Johnson, Rebecca E.;Kendall, Richard;Kim, Joseph L.;Long, Alexander M.;McGowan, David;Morrison, Michael;Olivieri, Philip R.;Patel, Vinod F.;Polverino, Anthony;Powers, David;Rose, Paul;Wang, Ling;Zhao, Huilin [Journal of Medicinal Chemistry,2007,vol. 50,# 4,p. 627 - 640]