4-Trifluoromethyl-5,6,7,8-tetrahydroquinazolin-2-ol synthesis
2synthesis methods
- Product Name:4-Trifluoromethyl-5,6,7,8-tetrahydroquinazolin-2-ol
- CAS Number:318258-14-9
- Molecular formula:C9H9F3N2O
- Molecular Weight:218.18
Yield:318258-14-9 57%
Reaction Conditions:
boron trifluoride diethyl etherate in isopropyl alcohol; for 21 h;Heating;Condensation;Cyclization;
References:
Sevenard;Khomutov;Koryakova;Sattarova;Kodess;Stelten;Loop;Lork;Pashkevich;Roschenthaler [Synthesis,2000,# 12,p. 1738 - 1748]