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350672-14-9

2-(Chloromethyl)-5-(4-fluorophenyl)-1,3,4-oxadiazole synthesis

7synthesis methods
499129-05-4 Synthesis
N''-(2-Chloroacetyl)-4-fluorobenzohydrazide

499129-05-4
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Yield:350672-14-9 74%

Reaction Conditions:

with trichlorophosphate for 2 h;Reflux;

References:

Sutherland, Hamish S.;Blaser, Adrian;Kmentova, Iveta;Franzblau, Scott G.;Wan, Baojie;Wang, Yuehong;Ma, Zhenkun;Palmer, Brian D.;Denny, William A.;Thompson, Andrew M. [Journal of Medicinal Chemistry,2010,vol. 53,# 2,p. 855 - 866] Location in patent:experimental part