4-(TRIFLUOROACETYLAMINO)-1-BUTANOL synthesis
- Product Name:4-(TRIFLUOROACETYLAMINO)-1-BUTANOL
- CAS Number:128238-43-7
- Molecular formula:C6H10F3NO2
- Molecular Weight:185.14
13325-10-5
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$10.00/1g
383-63-1
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$10.00/25g
128238-43-7
12 suppliers
$97.10/1ml
Yield:128238-43-7 100%
Reaction Conditions:
in ethanol at 20;
Steps:
(1) 4-trifluoroacetamidobutanol (Compound 11)
(1)
4-trifluoroacetamidobutanol (Compound 11)
A solution (100 ml) of 4-aminobutanol (2.50 g, 28.05 mmol) and trifluoroacetic acid ethyl ester (19.92 g, 140.26 mmol) in ethanol was stirred at room temperature overnight.
The reaction mixture was concentrated under reduced pressure to give 4-trifluoroacetamidobutanol (11) (5.44 g, q.) as a colorless syrup.
References:
US9404108,2016,B2 Location in patent:Page/Page column 30; 34
13325-10-5
314 suppliers
$10.00/1g
407-25-0
470 suppliers
$9.00/1g
128238-43-7
12 suppliers
$97.10/1ml
13325-10-5
314 suppliers
$10.00/1g
431-47-0
295 suppliers
$10.00/5g
128238-43-7
12 suppliers
$97.10/1ml