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71546-51-5

4-hydroxy-4(2-hydroxymethylphenyl)-1-piperidine carboxylat synthesis

1synthesis methods
-

Yield:-

Reaction Conditions:

with n-butyllithium1.) n-hexane, THF, Et2O, -78 deg C, 1 h, 2.) n-hexane, THF, Et2O, RT, 16 h;Yield given. Multistep reaction;

References:

Kubota, Hirokazu;Fujii, Masahiro;Ikeda, Ken;Takeuchi, Makoto;Shibanuma, Tadao;Isomura, Yasuo [Chemical and Pharmaceutical Bulletin,1998,vol. 46,# 2,p. 351 - 354]

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