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ChemicalBook CAS DataBase List 5-nitro-1'-((2-(triMethylsilyl)ethoxy)Methyl)-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one
879132-49-7

5-nitro-1'-((2-(triMethylsilyl)ethoxy)Methyl)-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one synthesis

8synthesis methods
879132-48-6 Synthesis
1-((2-(triMethylsilyl)ethoxy)Methyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one

879132-48-6
70 suppliers
$13.00/100mg

6425-66-7 Synthesis
1,2-Bis(bromomethyl)-4-nitrobenzene

6425-66-7
57 suppliers
$65.00/100mg

5-nitro-1'-((2-(triMethylsilyl)ethoxy)Methyl)-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

879132-49-7
7 suppliers
inquiry

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Yield:879132-49-7 70%

Reaction Conditions:

with caesium carbonate in N,N-dimethyl-formamide;

References:

Stump, Craig A.;Bell, Ian M.;Bednar, Rodney A.;Bruno, Joseph G.;Fay, John F.;Gallicchio, Steven N.;Johnston, Victor K.;Moore, Eric L.;Mosser, Scott D.;Quigley, Amy G.;Salvatore, Christopher A.;Theberge, Cory R.;Blair Zartman;Zhang, Xu-Fang;Kane, Stefanie A.;Graham, Samuel L.;Vacca, Joseph P.;Williams, Theresa M. [Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,# 1,p. 214 - 217] Location in patent:scheme or table

879132-47-5 Synthesis
3,3-dibroMo-1-((2-(triMethylsilyl)ethoxy)Methyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one

879132-47-5
22 suppliers
$557.00/1g

5-nitro-1'-((2-(triMethylsilyl)ethoxy)Methyl)-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

879132-49-7
7 suppliers
inquiry