Duloxetine Impurity 4 synthesis

3synthesis methods

315-53-7 Synthesis

Yield:1000386-62-8 60 %

Reaction Conditions:

with sodium carbonate in acetonitrile at 100;Inert atmosphere;

References:

Feng, Cong-Cong;Zhang, Song-Lin [Organic and Biomolecular Chemistry,2022,vol. 21,# 4,p. 728 - 731] Location in patent:supporting information

321-38-0 Synthesis

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