ETHYL 2,2-DIETHOXYPROPIONATE synthesis
- Product Name:ETHYL 2,2-DIETHOXYPROPIONATE
- CAS Number:7476-20-2
- Molecular formula:C9H18O4
- Molecular Weight:190.24
617-35-6
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$5.00/10g
122-51-0
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$10.00/5ml
7476-20-2
34 suppliers
$60.00/100mg
109-94-4
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Yield: 61%
Reaction Conditions:
with toluene-4-sulfonic acid in ethanol
Steps:
3.a (a)
(a) 1st Stage-Preparation of Ethyl Pyruvate Diethyl Acetal Ethyl pyruvate (22ml, 0.19 mmol) was dissolved in ethanol (30 ml) and to this was added triethyl orthoformate (35 ml) and p-toluenesulphonic acid (0.5 g) and the mixture stirred at 60° C. for 15 minutes. The temperature was slowly increased to 80° C. and the ethyl formate produced in the reaction distilled off After removal of all the ethyl formate (5 hours) the remaining mixture was neutralised with triethanolamine (0.5 ml). Ethanol was removed in vacuo and the remaining liquor distilled under reduced pressure yielding the title compound as a clear colourless liquid (30.78 g, 61%), b.p. 80-83° C. at 15 mm Hg.
References:
Newcastle University Ventures Limited US6297250, 2001, B1
617-35-6
562 suppliers
$5.00/10g
122-51-0
519 suppliers
$10.00/5ml
7476-20-2
34 suppliers
$60.00/100mg
64-17-5
760 suppliers
$10.00/50g
127-17-3
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$5.00/10g
126-84-1
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$39.00/5mL
7476-20-2
34 suppliers
$60.00/100mg
64-17-5
760 suppliers
$10.00/50g
22121-86-4
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7476-20-2
34 suppliers
$60.00/100mg
617-35-6
562 suppliers
$5.00/10g
64-17-5
760 suppliers
$10.00/50g
7476-20-2
34 suppliers
$60.00/100mg