Flutolanil synthesis
- Product Name:Flutolanil
- CAS Number:66332-96-5
- Molecular formula:C17H16F3NO2
- Molecular Weight:323.31
41406-00-2
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$21.21/1gm:
312-94-7
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$9.00/1g
66332-96-5
93 suppliers
$180.00/500mg
Yield:66332-96-5 91%
Reaction Conditions:
with triethylamine hydrochloride;triethylamine in tetrahydrofuran;(2S)-N-methyl-1-phenylpropan-2-amine hydrate;
Steps:
1 EXAMPLE 1
EXAMPLE 1 Synthesis of o-trifluoromethyl-m'-isopropoxybenzoic anilide. To a tetrahydrofuran solution containing 1.5 g (0.01 mole) of m-isopropoxyaniline and 1.2 g (0.011 mole) of triethylamine, while being cooled in ice water, was added slowly 2.3 g (0.011 mole) of o-trifluoromethylbenzoyl chloride. After having been stirred for 2 hours at room temperature, the reaction mixture was freed from triethylamine hydrochloride by filtration and then from the solvent by distillation under reduced pressure. The residue was recrystallized from n-hexane to obtain 2.9 g (91% yield) of the intended product melting at 95° to 97° C.
References:
US4093743,1978,A
201230-82-2
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41406-00-2
117 suppliers
$21.21/1gm:
444-29-1
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$10.00/1g
66332-96-5
93 suppliers
$180.00/500mg