Methyl 5-ethynylpyridine-2-carboxylate synthesis
- Product Name:Methyl 5-ethynylpyridine-2-carboxylate
- CAS Number:17880-61-4
- Molecular formula:C9H7NO2
- Molecular Weight:161.16
30766-11-1
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17880-61-4
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Yield:-
Steps:
Multi-step reaction with 3 steps
1: benzene; methanol / 1 h / 20 °C / Inert atmosphere
2: N-ethyl-N,N-diisopropylamine / copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 14 h / 70 °C / Sealed vessel; Inert atmosphere
3: potassium carbonate; methanol / 0.67 h / 20 °C / Inert atmosphere
References:
DUKE UNIVERSITY;ZHOU, Pei;TOONE, Eric, J. WO2012/31298, 2012, A2
29682-15-3
285 suppliers
$8.00/1g
17880-61-4
54 suppliers
$44.00/100mg