Nilotinib genotoxic impurity 3 synthesis
- Product Name:Nilotinib genotoxic impurity 3
- CAS Number:915711-42-1
- Molecular formula:C19H17F3N4O
- Molecular Weight:374.36
1449570-25-5
1 suppliers
inquiry
915711-42-1
24 suppliers
inquiry
Yield:915711-42-1 80%
Reaction Conditions:
Stage #1: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-nitrobenzamide hydrochloridewith tin(ll) chloride in methanol at 10;Reflux;
Stage #2: with sodium hydroxide in methanol;water at 10 - 15; for 2 h;
References:
Amala;Bhujanga Rao;Sreenivas;Dubey [Asian Journal of Chemistry,2013,vol. 25,# 8,p. 4599 - 4602]
1157857-29-8
13 suppliers
inquiry
915711-42-1
24 suppliers
inquiry
96-98-0
369 suppliers
$8.00/10g
915711-42-1
24 suppliers
inquiry
10397-30-5
94 suppliers
$58.20/10ml
915711-42-1
24 suppliers
inquiry
641571-11-1
350 suppliers
$9.00/1g
915711-42-1
24 suppliers
inquiry