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1211825-25-0

1211825-25-0 Structure

1211825-25-0 Structure
IdentificationBack Directory
[Name]

1-Pyrrolidinecarboxamide, 2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-
[CAS]

1211825-25-0
[Synonyms]

ZN27
ZN-27
ZN 27
ZINC40099027
1-Pyrrolidinecarboxamide, 2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-
[Molecular Formula]

C23H26F3N3O3
[MOL File]

1211825-25-0.mol
[Molecular Weight]

449.47
Chemical PropertiesBack Directory
[Boiling point ]

613.0±55.0 °C(Predicted)
[density ]

1.308±0.06 g/cm3(Predicted)
[solubility ]

DMSO: Sparingly soluble: 1-10 mg/ml
[form ]

Solid
[pka]

12.12±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

ZINC40099027 is a FAK activator. ZINC40099027 promotes FAK phosphorylation, inducing mucosal healing in murine models. ZINC40099027 can be used for Gastroduodenal ulcer disease research[1].
[References]

[1] Wang Q, et al. Discovery of Novel Small-Molecule FAK Activators Promoting Mucosal Healing. ACS Med Chem Lett. 2021 Feb 16;12(3):356-364. DOI:10.1021/acsmedchemlett.0c00311
Spectrum DetailBack Directory
[Spectrum Detail]

1-Pyrrolidinecarboxamide, 2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-(1211825-25-0)1HNMR
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