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1334172-58-5

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1334172-58-5 Structure

1334172-58-5 Structure
IdentificationBack Directory
[Name]

Biotin-PEG4-PFP ester
[CAS]

1334172-58-5
[Synonyms]

Biotin-PEG4-PFP ester
[Molecular Formula]

C27H36F5N3O8S
[MDL Number]

MFCD13184979
[MOL File]

1334172-58-5.mol
[Molecular Weight]

657.65
Chemical PropertiesBack Directory
[Boiling point ]

804.9±65.0 °C(Predicted)
[density ]

1.321±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

13.90±0.40(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P261
[HS Code ]

3404200000
Hazard InformationBack Directory
[Uses]

Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Cleavable Linker
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
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