ChemicalBook--->CAS DataBase List--->189209-28-7

189209-28-7

189209-28-7 Structure

189209-28-7 Structure
IdentificationBack Directory
[Name]

Biotin-PEG5-NH-Boc
[CAS]

189209-28-7
[Synonyms]

Biotin-PEG5-NH-Boc
tert-Butyl (19-oxo-23-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9,12,15-pentaoxa-18-azatricosyl)carbamate
5,8,11,14,17-Pentaoxa-2,20-diazapentacosanoic acid, 25-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-21-oxo-, 1,1-dimethylethyl ester
[Molecular Formula]

C27H50N4O9S
[MDL Number]

MFCD30527395
[MOL File]

189209-28-7.mol
[Molecular Weight]

606.77
Chemical PropertiesBack Directory
[Boiling point ]

803.9±65.0 °C(Predicted)
[density ]

1.147±0.06 g/cm3(Predicted)
[pka]

12.23±0.46(Predicted)
Hazard InformationBack Directory
[Description]

Biotin-PEG5-NH-Boc is a Biotin molecule with a Boc protected amine moiety.
[Uses]

Biotin-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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