| Identification | Back Directory | [Name]
Pyrene -PEG5-propargyl | [CAS]
1817735-33-3 | [Synonyms]
Pyrene -PEG5-propargyl
1-Pyrenecarboxamide, N-3,6,9,12,15-pentaoxaoctadec-17-yn-1-yl- | [Molecular Formula]
C30H33NO6 | [MDL Number]
MFCD29042352 | [MOL File]
1817735-33-3.mol | [Molecular Weight]
503.59 |
| Chemical Properties | Back Directory | [Boiling point ]
696.3±55.0 °C(Predicted) | [density ]
1.210±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DMF, DCM | [pka]
14.19±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
Pyrene-PEG5-propargyl is a pyrene labeled PEG linker containing an propargyl group, which enables Click Chemistry labeling. The hydrophilic PEG linker can increase water solubility and this reagent will be ideal for antibody, protein or probe conjugation. | [Uses]
Pyrene-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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