| Chemical Properties | Back Directory | [Boiling point ]
1264.4±65.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
9.38±0.15(Predicted) |
| Hazard Information | Back Directory | [Description]
PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).
| [Uses]
PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab)[1]. | [References]
[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1. |
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MedChemExpress
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021-58955995 |
| Website: |
www.medchemexpress.com |
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