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2360533-90-8

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2360533-90-8 Structure

2360533-90-8 Structure
IdentificationBack Directory
[Name]

PROTAC IRAK4 degrader-1
[CAS]

2360533-90-8
[Synonyms]

PROTAC IRAK4 degrader-1
[Molecular Formula]

C44H39F3N12O7
[MDL Number]

MFCD34469671
[Molecular Weight]

904.85
Chemical PropertiesBack Directory
[density ]

1.61±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

10.74±0.40(Predicted)
[color ]

White to yellow
Hazard InformationBack Directory
[Biological Activity]

PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].
[References]

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
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