| Identification | Back Directory | [Name]
PROTAC ERRα Degrader-1 | [CAS]
2306388-84-9 | [Synonyms]
PROTAC ERRα Degrader-1
PROTAC ERRα Degrader-1 | [Molecular Formula]
C54H49Cl2F6N7O8 | [MDL Number]
MFCD32197286 | [MOL File]
2306388-84-9.mol | [Molecular Weight]
1108.91 |
| Chemical Properties | Back Directory | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
11.80±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
ERRα Degrader-1 is a Novel PROTAC Estrogen-related Receptor α (ERRα) Degrader. | [Uses]
PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an PROTAC estrogen-related receptor alpha (ERRa) degrader[1]. | [IC 50]
ERRα; MDM2 | [storage]
Store at -20°C | [References]
[1] Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772. DOI:10.1021/acsmedchemlett.9b00025 |
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