ChemicalBook--->CAS DataBase List--->2079056-43-0

2079056-43-0

2079056-43-0 Structure

2079056-43-0 Structure
IdentificationBack Directory
[Name]

PROTAC FKBP Degrader-3
[CAS]

2079056-43-0
[Synonyms]

PROTAC FKBP Degrader-3
[Molecular Formula]

C68H90N6O17S
[MDL Number]

MFCD32693909
[MOL File]

2079056-43-0.mol
[Molecular Weight]

1295.54
Chemical PropertiesBack Directory
[Boiling point ]

1297.9±65.0 °C(Predicted)
[density ]

1.233±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 25 mg/mL (19.30 mM)
[form ]

Solid
[pka]

13.54±0.46(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an von Hippel-Lindau binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].
[IC 50]

VHL; FKBP
[storage]

Store at -20°C
[References]

[1] Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578. DOI:10.1021/acschembio.7b00485
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