| Identification | Back Directory | [Name]
Carboxy Fluorescein-PEG12-NHS | [CAS]
2246595-66-2 | [Synonyms]
Carboxy Fluorescein-PEG12-NHS | [MDL Number]
MFCD28505578 |
| Hazard Information | Back Directory | [Description]
Carboxy Fluorescein-PEG12-NHS is a fluorescein labeled PEG linker containing a NHS group, which enables labeling for antibodies and other purified proteins at primary amines (lysine side chains). The hydrophilic PEG spacer arm increases solubility in aqueous media. | [Uses]
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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