ChemicalBook--->CAS DataBase List--->3430-27-1

3430-27-1

3430-27-1 Structure

3430-27-1 Structure
IdentificationMore
[Name]

3-Amino-4-methylpyridine
[CAS]

3430-27-1
[Synonyms]

3-AMINO-4-METHYLPYRIDINE
3-AMINO-4-PICOLINE
4-METHYL-3-PYRIDINAMINE
4-METHYLPYRIDIN-3-AMINE
4-METHYL-PYRIDIN-3-YLAMINE
IFLAB-BB F1957-0029
3-AMINO-4-METHYLPYRIDINE 98%
3-Pyridinamine, 4-methyl-
3-Amino-4-methylryridine
3-Amino-4-methylpyridine 98+%
3-Pyridinamine,4-methyl-(9CI)
5-Amino-3-bromo-4,6-dimethyl Pyridine
4-METHYL-3-AMINOPYRIDINE
3-AMINO-4-METHYLPYRIDINE (3-AMINO-4-PICOLINE)
6-methylpyridin-amine
3-Amino-4-picoline ,99%
4-Methylpyridine-3-amine
[EINECS(EC#)]

608-968-1
[Molecular Formula]

C6H8N2
[MDL Number]

MFCD00128871
[Molecular Weight]

108.14
[MOL File]

3430-27-1.mol
Chemical PropertiesBack Directory
[Melting point ]

102-107 °C
[Boiling point ]

254°C
[density ]

1.0275 (estimate)
[refractive index ]

1.5560 (estimate)
[Fp ]

254°C
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

Chloroform, Ethyl Acetate, Methanol
[form ]

powder to crystal
[pka]

6.83±0.18(Predicted)
[color ]

White to Brown
[Sensitive ]

Hygroscopic
[Detection Methods]

HPLC,NMR,GC
[BRN ]

107792
[InChI]

InChI=1S/C6H8N2/c1-5-2-3-8-4-6(5)7/h2-4H,7H2,1H3
[InChIKey]

IBKMZYWDWWIWEL-UHFFFAOYSA-N
[SMILES]

C1=NC=CC(C)=C1N
[CAS DataBase Reference]

3430-27-1(CAS DataBase Reference)
[NIST Chemistry Reference]

3-Pyridinamine, 4-methyl-(3430-27-1)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H318-H335
[Precautionary statements ]

P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
[Hazard Codes ]

T,Xn
[Risk Statements ]

R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
R41:Risk of serious damage to eyes.
R37/38:Irritating to respiratory system and skin .
R22:Harmful if swallowed.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
[RIDADR ]

2811
[WGK Germany ]

3
[Hazard Note ]

Toxic
[HazardClass ]

6.1
[PackingGroup ]

III
[HS Code ]

29333990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

2-Chloro-4-methyl-3-nitropyridine-->4-Methyl-3-nitropyridine-->3-Bromo-4-methylpyridine-->Ethyl acetate-->Hydrogen
[Preparation Products]

3-Amino-2-bromo-4-picoline-->3-Amino-2-chloro-4-methylpyridine-->3-Fluoropyridine-4-carboxylic acid-->6-Azaindole-->4-Methyl-3-methylaminopyridine-->3-Bromo-4-methylpyridine-->1H-Pyrazolo[3,4-c]pyridine, 1-acetyl- (9CI)-->2-tert-Butyl-1H-pyrrolo[2,3-c]pyridine
Hazard InformationBack Directory
[Chemical Properties]

White to brown crystal or powder
[Definition]

3-amido-4-methylpyridine could synthesize 2-chlorin-3-amido-4-methyl pyridine through chlorination, the key intermediate of synthesizing anti-AIDS pharmaceutical nevirapine.
[Synthesis]

3-Amino-4-methylpyridine could be synthesized through the reaction of 4-methylpyridine and N2O5.
[References]

[1] Patent: EP1428824, 2004, A1. Location in patent: Page 42
[2] Tetrahedron Letters, 2010, vol. 51, # 5, p. 786 - 789
[3] Journal of Heterocyclic Chemistry, 2001, vol. 38, # 1, p. 99 - 104
[4] Bulletin de la Societe Chimique de France, 1992, # 1, p. 79 - 84
[5] Chemische Berichte, 1927, vol. 60, p. 2108
Questions And AnswerBack Directory
[Application]

3-Amino-4-methylpyridine is an important pharmaceutical and chemical intermediate, widely used in the synthesis and research and development of pharmaceuticals, pesticides, and veterinary drugs, and has high application and market value.
Spectrum DetailBack Directory
[Spectrum Detail]

3-Amino-4-methylpyridine(3430-27-1)MS
3-Amino-4-methylpyridine(3430-27-1)1HNMR
3-Amino-4-methylpyridine(3430-27-1)13CNMR
3-Amino-4-methylpyridine(3430-27-1)IR1
3-Amino-4-methylpyridine(3430-27-1)IR2
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

3-Amino-4-methylpyridine, 98%(3430-27-1)
[Sigma Aldrich]

3430-27-1(sigmaaldrich)
[TCI AMERICA]

3-Amino-4-picoline,>98.0%(GC)(T)(3430-27-1)
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