| Identification | More | [Name]
2,4-Dimethoxypyrimidine | [CAS]
3551-55-1 | [Synonyms]
2,4-DIMETHOXYPYRIMIDINE
Pyrimidine, 2,4-dimethoxy-(6CI,7CI,8CI,9CI)
2,4-DIMETHOXYPYRIMIDINE 98%
2,4-dimethoxypyrimdine
2,4-Dimethoxypyrimidine, 98+%
2,4-Dimethoxypyrimidine ,97%
2,4-DIMETHOXYPYRIMIDINE, 99+% | [Molecular Formula]
C6H8N2O2 | [MDL Number]
MFCD00056028 | [Molecular Weight]
140.14 | [MOL File]
3551-55-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to light brown liquid | [Melting point ]
17°C | [Boiling point ]
204-205 °C (lit.) | [density ]
1.1501 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.502(lit.)
| [Fp ]
198-200 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Oil | [pka]
2.69±0.20(Predicted) | [color ]
Clear Colorless | [Detection Methods]
HPLC | [InChI]
1S/C6H8N2O2/c1-9-5-3-4-7-6(8-5)10-2/h3-4H,1-2H3 | [InChIKey]
KEVRHVMWBKFGLO-UHFFFAOYSA-N | [SMILES]
COc1ccnc(OC)n1 | [CAS DataBase Reference]
3551-55-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes .
S36/37:Wear suitable protective clothing and gloves .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
NA 1993 / PGIII | [WGK Germany ]
3
| [HS Code ]
29335990 | [Storage Class]
10 - Combustible liquids |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to light brown liquid | [Uses]
2,4-Dimethoxypyrimidine, is a versatile building block used in synthesis of various chemical compounds, such as derivatives of Cytidine (C998300). | [Synthesis]
The general procedure for the synthesis of 2,4-dimethoxypyrimidine from 6-chloro-2,4-dimethoxypyrimidine was as follows:
1. 6-Chloro-2,4-dimethoxypyrimidine (0.66 mmol) was dissolved in anhydrous THF (13.2 mL) under argon protection and degassed by drumming argon for a few minutes.
2. Catalyst PdCl2 (dppf) (27.0 mg, 0.033 mmol, 5.0 mol%), TMEDA (0.130 g, 1.12 mmol, 1.7 equiv), and reductant NaBH4 (42.4 mg, 1.12 mmol, 1.7 equiv) were added sequentially.
3. The reaction mixture was stirred at room temperature and under argon atmosphere for an appropriate time.
4. After completion of the reaction, post-treatment was carried out according to standard methods. | [References]
[1] Journal of Molecular Catalysis A: Chemical, 2014, vol. 393, p. 191 - 209
[2] Journal of Organic Chemistry, 1955, vol. 20, p. 829,833,835 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
|