| Identification | Back Directory | [Name]
geissoschizine methylether | [CAS]
60314-89-8 | [Synonyms]
geissoschizine methylether
geissoschizine methylether USP/EP/BP
Geissoschizine methyl ether, HPLC≥98%
(16E,19E)-16,17,19,20-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester
(Z)-methyl 2-((2S,12bS,E)-3-ethylidene-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate
Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethylidene-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αZ,2S,3E,12bS)- | [Molecular Formula]
C21H26N2O3 | [MDL Number]
MFCD30725476 | [MOL File]
60314-89-8.mol | [Molecular Weight]
366.45 |
| Chemical Properties | Back Directory | [Boiling point ]
542.0±50.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
18.02±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Uncaria. | [Uses]
Geissoschizine methyl ether has anti-platelet aggregation and anti-thrombotic, blood pressure-lowering effects. | [Biological Activity]
Geissoschizine methyl ether, an alkaloid compound discovered by the Uncaria hook, is also the main active ingredient in the psychoactive Yokukansan. It is a potent 5-HT1A receptor agonist. | [target]
| [IC 50]
5-HT1A Receptor |
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