| Identification | Back Directory | [Name]
1-METHYL-BIO | [CAS]
667463-95-8 | [Synonyms]
MEBIO
Me6BIO
1-METHYL-BIO
GSK-3 INHIBITOR XIV, CONTROL
(2'Z,3'E)-6-Bromo-1-methylindirubin-3'-oxime
2H-Indol-2-one, 6-bromo-3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-1-methyl-, (3Z)-
Glycogen synthase kinase-3,CDK,GSK-3,Aryl Hydrocarbon Receptor (AhR),Glycogen synthase kinase 3,Inhibitor,inhibit,AhR,Agonist,Cyclin dependent kinase,Aryl Hydrocarbon Receptor,MeBIO | [Molecular Formula]
C17H12BrN3O2 | [MDL Number]
MFCD09037537 | [MOL File]
667463-95-8.mol | [Molecular Weight]
370.2 |
| Hazard Information | Back Directory | [Uses]
MeBIO is an indirubin, which has been suggested to possess the structural basis for a potent and selective inhibitor of glycogen synthase kinase-3 (GSK3) and cyclin-dependent kinases. | [IC 50]
GSK-3: 44 μM (IC50); Cdk1/cyclin B: 55 μM (IC50); Cdk5/p25: >100 μM (IC50) | [storage]
Store at +4°C |
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