ChemicalBook >> CAS DataBase List >>Cobalamine
Cobalamine
- CAS No.
- 68-19-9
- Chemical Name:
- Cobalamine
- Synonyms
- CYANOCOBALAMIN;Vb12;METHYLCOBALAMIN;CYANOCOBALAMINE;hemomin;cyanocobalamin (b12);COBALAMINE;hydroxycobalamin chloride;VIT B12;depinar
- CBNumber:
- CB00129347
- Molecular Formula:
- C63H88CoN14O14P
- Molecular Weight:
- 1355.37
- MDL Number:
- MFCD00151092
- MOL File:
- 68-19-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-31 17:49:05
| Product description | Number | Pack Size | Price |
| Cyanocobalamin for system suitability CRS European Pharmacopoeia (EP) Reference Standard | Y0002204 | 15 mg | $180 |
| Cyanocobalamin for peak identification CRS European Pharmacopoeia (EP) Reference Standard | Y0002203 | 15 mg | $180 |
| Cyanocobalamin (Vitamin B12) solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | V-019 | 1mL | $91 |
| Cyanocobalamin pharmaceutical secondary standard, certified reference material | PHR1234 | 100 mg | $142 |
| Cyanocobalamin meets USP testing specifications | C3607 | 5g | $870 |
| More product size | |||
| Melting point | >300°C |
|---|---|
| alpha | 23656 -59 ± 9° (dil aq soln) |
| Boiling point | >300 °C |
| bulk density | 450-600kg/m3 |
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in acetone. The anhydrous substance is very hygroscopic. |
| pka | pKa 3.28±0.04(H2O,D2O t=23±0.5 Iunspecied) (Uncertain) |
| form | Crystalline Powder or Crystals |
| color | Red to dark red |
| PH | 6.0 (20°C, 1g/L in H2O) |
| Odor | dark red cryst. or powd., odorless and tasteless |
| biological source | synthetic ((organic)) |
| Water Solubility | Soluble |
| Sensitive | Hygroscopic |
| Merck | 14,10014 |
| BRN | 4122889 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| Stability | Hygroscopic. Keep cold and dry. |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChIKey | RMRCNWBMXRMIRW-WZHZPDAFSA-L |
| LogP | 3.570 (est) |
| SCOGS (Select Committee on GRAS Substances) | Vitamin B12 (cyanocobalamin) |
| Substances Added to Food (formerly EAFUS) | VITAMIN B-12 |
| NCI Dictionary of Cancer Terms | cyanocobalamin |
| FDA UNII | P6YC3EG204 |
| NCI Drug Dictionary | Berubigen |
| ATC code | B03BA01,B03BA51 |
| EPA Substance Registry System | Vitamin B12 (68-19-9) |
| UNSPSC Code | 41116107 |
| NACRES | NA.79 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P260-P280-P301+P310-P311 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | ||||||||||
| WGK Germany | WGK 1 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2936260000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazardous Substances Data | 68-19-9(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 intravenous in mouse: 2gm/kg | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Cobalamine price More Price(97)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0002204 | Cyanocobalamin for system suitability CRS European Pharmacopoeia (EP) Reference Standard | 68-19-9 | 15 mg | $180 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0002203 | Cyanocobalamin for peak identification CRS European Pharmacopoeia (EP) Reference Standard | 68-19-9 | 15 mg | $180 | 2026-04-30 | Buy |
| Sigma-Aldrich | V-019 | Cyanocobalamin (Vitamin B12) solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 68-19-9 | 1mL | $91 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR1234 | Cyanocobalamin pharmaceutical secondary standard, certified reference material | 68-19-9 | 100 mg | $142 | 2026-04-30 | Buy |
| Sigma-Aldrich | C3607 | Cyanocobalamin meets USP testing specifications | 68-19-9 | 5g | $870 | 2026-04-30 | Buy |
Cobalamine Chemical Properties,Uses,Production
Description
Cobalamine is a synthetic compound of vitamin B12 used to treat vitamin deficiencies. Chemically, cyanocobalamin is classified as a "corrinoid," representing a crystallizable cobalt complex. The name "cyanocobalamin" is derived from including a cyanide group within the molecule. Cyanocobalamin is approved by the United States Food and Drug Administration (FDA) for pernicious anemia, malabsorption, atrophic gastritis, gastrectomy, Helicobacter pylori infection, and other conditions.
Uses
Cyanocobalamin injection is used to treat and prevent a lack of vitamin B12 that may be caused by any of the following: pernicious anemia (lack of a natural substance needed to absorb vitamin B12 from the intestine); certain diseases, infections, or medications that decrease the amount of vitamin B12 absorbed from food; or a vegan diet (strict vegetarian diet that does not allow any animal products, including dairy products and eggs). Cyanocobalamin injection is in a class of medications called vitamins. Because it is injected straight into the bloodstream, it can be used to supply vitamin B12 to people who cannot absorb this vitamin through the intestine.
Side effects
Shortness of breath (even with mild exertion), swelling, rapid weight gain. Pulmonary edema, congestive heart failure, peripheral vascular thrombosis. Hypokalemia--leg cramps, irregular heartbeats, tingling/numbness, muscle weakness, or limp feeling.
Cobalamine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 1216)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9037 | 58 |
| TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 | yuxin@yuxchem.com | China | 167 | 58 |
| Zibo Wei Bin Import & Export Trade Co. Ltd. | +86-0533-2091136 +86-13355255566 | ziboweibinmaoyi@163.com | China | 100 | 58 |
| Watson Biotechnology Co.,Ltd | +86-18186686046 | sales01@watsonbiotech.cn | China | 5731 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019; +86-15383190639 | admin@86-ss.com | China | 996 | 58 |
| Chongqing Soarwin Technology Co., Ltd | +86-15790943001 | crystal@sorawin.cn | China | 419 | 58 |
| Hebei Dangtong Import and export Co LTD | +86-86-4001020630 +86-13910575315 | admin@hbdangtong.com | China | 996 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3955 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5838 | 58 |
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Related Qustion
Ask a questionQ:What are the causes of elevated vitamin B12 levels?STAR - Apr 3，2026
A:Elevated vitamin B12 levels may be caused by supplements, liver disease, kidney disease or myeloid malignancies. One potential benign cause of such elevations is megalobin, a complex formed by vitamin B12, trans-cobalamin and immunoglobulin. Although this complex is biologically inactive, it can still lead to elevated plasma vitamin B12 levels due to its reduced clearance. Persistent and unexplained elevated vitamin B12 levels may lead to patients undergoing invasive diagnostic procedures, including bone marrow biopsy. However, giant vitamin B12 can be detected using the polyethylene glycol precipitation method, thereby avoiding unnecessary diagnostic procedures, including bone marrow aspiration.
Q:Can furu products be used to supplement daily vitamin B12 requirements?STAR - Apr 3，2026
A:No. Although vitamin B12 has been reported to be present in ‘fermented tofu’ (furu), a traditional Chinese fermented tofu product, the levels are not high. Recent research indicates that grey furu has the highest vitamin B12 content (approximately 1.1 μg/100 g), whilst the levels in other products are all below 0.4 μg/100 g. Furthermore, only about 9% of the total vitamin B12 in grey furu is bioactive, with the remainder identified as inactive porphyrin compounds. Other products exhibit similar characteristics. These findings suggest that, although grey furu may provide small amounts of bioactive vitamin B12, commercially available furu products are not a reliable source of vitamin B12.
View Lastest Price from Cobalamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-21 | Sodium tetraborate pentahydrate
12179-04-3
|
1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
-
- Sodium tetraborate pentahydrate
12179-04-3
- 99%
- Anhui Ruihan Technology Co., Ltd
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VIT B12
CYANOCOBALAMIN USP CRYSTAL
a-(5,6-dimethylbenzimidazolyl)-cobalamidecyanide
α-(5,6-Dimethylbenzimidazolyl)cyanocobamide, CN-Cbl, Cyanocob(III)alamin, Cyanocobalamin, VitaminB12
α-(5,6-Dimethylbenzimidazolyl)cyanocobamide, CN-Cbl, Cyanocob(III)alamin, Cyanocobalamin
ANTIANEMIC VITAMIN B
EXTRINSIC FACTOR
CYANOCOB(III)ALAMIN
CYTACON
5,6-dimethyl-1-(3-o-phosphono-alpha-d-ribofuranosyl)-1h-benzimidazolmonoes
5,6-dimethylbenzimidazolylcobamidecyanide
5,6-dimethylbenzimidazolyl-co-cyanocobamide
alpha-5,6-dimethyl-1h-benzimidazolyl-cobamidcyanide
anacobin
berubigen
betalin-12
betalin12crystalline
betaline-12
betolvex
bevatine-12
b-twelve
