IBUPROFEN SODIUM SALT
- CAS No.
- 31121-93-4
- Chemical Name:
- IBUPROFEN SODIUM SALT
- Synonyms
- ibuprofensodium;Einecs 250-477-6;Sodium ibuprofen;IBUPROFEN SODIUM SALT;(±)-Ibuprofen-d3, SodiuM Salt;(±)-Ibuprofen-d3 (sodium salt);p-isobutylhydratropicacidsodiumsalt;p-isobutyl-hydratropicacisodiumsalt;sodiuM 2-(4-isobutylphenyl)propanoate;sodium 2-(4-isobutylphenyl)propionate
- CBNumber:
- CB0116983
- Molecular Formula:
- C13H17NaO2
- Molecular Weight:
- 228.26
- MDL Number:
- MFCD00133414
- MOL File:
- 31121-93-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Ibuprofen sodium salt analytical standard, ≥98% (GC) | I1892 | 100g | $205 |
| Ibuprofen sodium salt analytical standard, ≥98% (GC) | I1892 | 500g | $756 |
| Ibuprofen sodium ≥98% | CS-0031024 | 500mg | $60 |
| Ibuprofen sodium ≥98% | CS-0031024 | 1g | $71 |
| Ibuprofen sodium ≥98% | CS-0031024 | 500mg | $60 |
| Melting point | 110-112 °C |
|---|---|
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | H2O: 100 mg/mL, may be clear to slightly hazy |
| form | Solid |
| color | White to Off-White |
| Water Solubility | H2O: 100mg/mL, clear to slightly hazy |
| Stability | Stable. Incompatible with strong oxidizing agents |
| Major Application |
forensics and toxicology pharmaceutical (small molecule) |
| InChI | 1S/C13H18O2.Na/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;/h4-7,9-10H,8H2,1-3H3,(H,14,15);/q;+1/p-1 |
| InChIKey | PTTPUWGBPLLBKW-UHFFFAOYSA-M |
| SMILES | [Na+].CC(C)Cc1ccc(cc1)C(C)C([O-])=O |
| CAS DataBase Reference | 31121-93-4 |
| EWG's Food Scores | 1 |
| FDA UNII | O0PJ4UZ01U |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H302-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | MU6641000 |
| Storage Class | 11 - Combustible Solids |
IBUPROFEN SODIUM SALT price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I1892 | Ibuprofen sodium salt analytical standard, ≥98% (GC) | 31121-93-4 | 100g | $205 | 2026-04-30 | Buy |
| Sigma-Aldrich | I1892 | Ibuprofen sodium salt analytical standard, ≥98% (GC) | 31121-93-4 | 500g | $756 | 2026-04-30 | Buy |
| ChemScene | CS-0031024 | Ibuprofen sodium ≥98% | 31121-93-4 | 500mg | $60 | 2026-06-04 | Buy |
| ChemScene | CS-0031024 | Ibuprofen sodium ≥98% | 31121-93-4 | 1g | $71 | 2026-06-04 | Buy |
| ChemScene | CS-0031024 | Ibuprofen sodium ≥98% | 31121-93-4 | 500mg | $60 | 2026-06-04 | Buy |
IBUPROFEN SODIUM SALT Chemical Properties,Uses,Production
Chemical Properties
white powder
Uses
Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][5][8].
Application
Ibuprofen sodium salt is a useful research chemical.
Biological Activity
Cyclooxygenase (COX) inhibitor th at has greater activity against COX-1 than against COX-2.
in vivo
Ibuprofen sodium (fed in animal feedings, 300 mg/kg, 14 days) reduces overall tumor growth and enhances anti-tumor immune characteristics without adverse autoimmune reactions in a model of postpartum breast cancer[5].
Ibuprofen sodium (subcutaneous injection, 60 mg/kg, every second day for 15 days) reduces the risk of neuropathy in a rat model of chronic Oxaliplatininduced peripheral neuropathy[6].
Ibuprofen sodium (oral administration, 20 mg/kg, every 12 hours, 5 doses total) decreases muscle growth (average muscle fiber cross-sectional area) without affecting regulation of supraspinatus tendon adaptions to exercise[7].
Ibuprofen sodium (oral administration, 35 mg/kg, twice daily) attenuates the Inflammatory response to pseudomonas aeruginosa in a rat model of chronic pulmonary infection[8].
| Animal Model: | Syngeneic (D2A1) orthotopic Balb/c mouse model of PPBC (postpartum)[5] |
| Dosage: | 300 mg/kg, daily for 14 days |
| Administration: | Fed in animal feedings (added to pulverized standard chow and mixed dry, then mixed with water, made into chow pellets and dried thoroughly) |
| Result: | Suppresed tumor growth, reduced presence of immature monocytes and increased numbers of T cells. Enhanced Th1 associated cytokines as well as promoted tumor border accumulation of T cells. |
| Animal Model: | Oxaliplatininduced peripheral neuropathy[6] |
| Dosage: | 60 mg/kg, every second day for 15 days |
| Administration: | Subcutaneous injection |
| Result: | Lowered sensory nerve conduction velocity (SNCV). |
IC 50
COX-1: 13 μM (IC50); COX-2: 370 μM (IC50)
References
[1] Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. DOI:10.1021/np970343j
[2] Hassan Akrami, et al. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015 May;36(5):3237-43. DOI:10.1007/s13277-014-2952-3
[3] Sharon M Rymut, et al. Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L317-27. DOI:10.1152/ajplung.00126.2016
[4] Emmanuelle Bignon, et al. Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process. Sci Rep. 2017 Aug 21;7(1):8885. DOI:10.1038/s41598-017-09406-8
[5] Nathan D Pennock, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6(1):98. DOI:10.1186/s40425-018-0406-y
[6] Thomas Krigrd, et al. Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy. Exp Brain Res. 2019 Oct;237(10):2645-2651. DOI:10.1007/s00221-019-05615-x
[7] Sarah Ilkhanipour Rooney, et al. Ibuprofen Differentially Affects Supraspinatus Muscle and Tendon Adaptations to Exercise in a Rat Model. Am J Sports Med. 2016 Sep;44(9):2237-45. DOI:10.1177/0363546516646377
[8] M W Konstan, et al. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis. 1990 Jan;141(1):186-92. DOI:10.1164/ajrccm/141.1.186
IBUPROFEN SODIUM SALT Preparation Products And Raw materials
IBUPROFEN SODIUM SALT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3959 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3373 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 | info@afinechem.com | China | 15080 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| Dingwang Technology (Wuhan) Co., Ltd. | +undefined-27-2786652399 +undefined13627115097 | market02@senwayer.com | China | 887 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
View Lastest Price from IBUPROFEN SODIUM SALT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Ibuprofen sodium
31121-93-4
|
10g | TargetMol Chemicals Inc. | ||||
 |
2026-07-15 | IBUPROFEN SODIUM SALT
31121-93-4
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-08-22 | IBUPROFEN SODIUM SALT
31121-93-4
|
1kg | 99% | 500kg | Dingwang Technology (Wuhan) Co., Ltd. |
-
- Ibuprofen sodium
31121-93-4
- $0.00
- TargetMol Chemicals Inc.
-
- IBUPROFEN SODIUM SALT
31121-93-4
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- IBUPROFEN SODIUM SALT
31121-93-4
- 99%
- Dingwang Technology (Wuhan) Co., Ltd.
