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2-(4-Methylphenyl)propanoic acid

2-(4-Methylphenyl)propanoic acid Structure
2-(4-Methylphenyl)propanoic acid structure
CAS No.
938-94-3
Chemical Name:
2-(4-Methylphenyl)propanoic acid
Synonyms
2-p-Tolylpropanoic acid;(2RS)-2-(4-METHYLPHENYL)PROPANOIC ACID;2-(P-TOLYL)PROPIONIC ACID;Ibuprofen-3;2-(4-MethyL;5932B+5242:5246;IBUPROFEN IMP D;2-(4-Methylphenyl)pr;IBUPROFEN IMPURITY D;Ibuprofen EP Impurity D
CBNumber:
CB1333307
Molecular Formula:
C10H12O2
Molecular Weight:
164.2
MDL Number:
MFCD01111378
MOL File:
938-94-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:37:17
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2-(4-Methylphenyl)propanoic acid Properties

Melting point 37-42 °C(lit.)
Boiling point 231.67°C (rough estimate)
Density 1.0041 (rough estimate)
refractive index 1.518-1.52
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 4.44±0.10(Predicted)
color White to Off-White
BRN 2251315
InChI InChI=1S/C10H12O2/c1-7-3-5-9(6-4-7)8(2)10(11)12/h3-6,8H,1-2H3,(H,11,12)
InChIKey KDYOFXPLHVSIHS-UHFFFAOYSA-N
SMILES C(C1C=CC(C)=CC=1)(C)C(=O)O
CAS DataBase Reference 938-94-3(CAS DataBase Reference)
FDA UNII 1635C8OCXW
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29163990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

2-(4-Methylphenyl)propanoic acid price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3321 (2RS)-2-(4-methylphenyl)propanoic acid certified reference material, pharmaceutical secondary standard 938-94-3 50MG $804 2026-04-30 Buy
Sigma-Aldrich 522449 α,4-Dimethylphenylacetic acid 97% 938-94-3 5g $151 2023-06-20 Buy
TCI Chemical M1352 (±)-2-(p-Tolyl)propanoic Acid min. 95.0 % 938-94-3 25G $56 2026-04-30 Buy
Biosynth FT28321 2-(p-Tolyl)propionic acid 938-94-3 250g $150 2026-06-04 Buy
Biosynth FT28321 2-(p-Tolyl)propionic acid 938-94-3 100g $150 2026-06-04 Buy
Product number Packaging Price Buy
PHR3321 50MG $804 Buy
522449 5g $151 Buy
M1352 25G $56 Buy
FT28321 250g $150 Buy
FT28321 100g $150 Buy

2-(4-Methylphenyl)propanoic acid Chemical Properties,Uses,Production

Chemical Properties

clear yellow liquid after melting

Uses

2-(p-Tolyl)propionic acid is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.

Uses

2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.

Synthesis Reference(s)

Synthesis, p. 231, 1984 DOI: 10.1055/s-1984-30784
Tetrahedron Letters, 36, p. 5641, 1995 DOI: 10.1016/0040-4039(95)01035-G

General Description

α,4-Dimethylphenylacetic acid is also referred to as 2-(4-methylphenyl)propanoic acid. It is an alkaline decomposition product of azalomycin-B, a macrolide antibiotic produced by Streptomyces hygroscopicus var. azalomyceticus. The reaction of pinonic acid with bromine in water affords 2-(4-methylphenyl)propanoic acid.

2-(4-Methylphenyl)propanoic acid synthesis

75920-45-5
938-94-3
Synthesis of 2-(4-Methylphenyl)propanoic acid from 2-(4-methylphenyl)propanenitrile

2-(4-Methylphenyl)propanoic acid Preparation Products And Raw materials

Raw materials

Benzene, 1-(1-bromoethyl)-4-methyl-, (-)- 2-(4-methylphenyl)propanenitrile Benzeneacetic acid, α-hydroxy-α,4-dimethyl- 2-(p-Tolyl)-propionic acid methyl ester 1-(1-Chloroethyl)-4-Methylbenzene
ethyl 2-p-tolylpropanoate 4-Methylstyrene Formic acid carbon monoxide Carbon dioxide
Iodomethane 4-Methylphenylacetic acid

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Preparation Products

3-(4-METHYLPHENYL)PROPIONIC ACID

2-(4-Methylphenyl)propanoic acid Suppliers

Global( 281)Suppliers
Supplier Tel Email Country ProdList Advantage
GUANGZHOU AANPHARM TECHNOLOGY CO.,LTD 020-86211473 13925088720 linda@aanpharm.com China 3641 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Supplier Advantage
GUANGZHOU AANPHARM TECHNOLOGY CO.,LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61
Beijing Ouhe Technology Co., Ltd 60
Accela ChemBio Co.,Ltd. 64
Shanghai Longsheng chemical Co.,Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60

View Lastest Price from 2-(4-Methylphenyl)propanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(4-Methylphenyl)propanoic acid pictures 2026-09-02 2-(4-Methylphenyl)propanoic acid
938-94-3
 $5.00 1KG 99% Henan Fengda Chemical Co., Ltd
Ibuprofen EP Impurity D pictures 2025-12-16 Ibuprofen EP Impurity D
938-94-3
 10mg 95%+ 100000 Moxin Chemicals
2-(4-Methylphenyl)propanoic acid pictures 2021-08-12 2-(4-Methylphenyl)propanoic acid
938-94-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

2-(4-Methylphenyl)propanoic acid Spectrum

2-(4-Methylphenyl)propanoic acid(938-94-3)1HNMR2-(4-Methylphenyl)propanoic acid(938-94-3)IR

938-94-3(2-(4-Methylphenyl)propanoic acid)Related Search:

Propionic acid METHYLSTYRENE Silicone oil (high temperature) 2,3-Dibromopropionic acid Chlorodimethylphenylsilane
Propionic anhydride 2-Chloropropionic acid DL-Phenylalanine (S)-(+)-2-Phenylpropionic acid 1-Methyl-4-(methylsulfonyl)-benzene
2,2-Bis(hydroxymethyl)propionic acid (S)-(+)-Ibuprofen Z-AIB-OH Ibuprofen (R)-(-)-IBUPROFEN
1-Hydroxyibuprofen 1-Oxo Ibuprofen Ibuprofen Ethyl Ester

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2-(p-Tolyl)propionic acidalpha,4-Dimethylphenylacetic acid 2-(4-Methylphenyl)pr 2-(p-Tolyl)propionic acid, 98% 5GR α-(p-Tolyl)propionic Acid α,4-DiMethylbenzeneacetic Acid Ibuprofen IMpurity-D -(EP) Ibuprofen EP Impurity D 5932B+5242:5246 2-(4-METHYLPHENYL)PROPA Ibuprofen-3 2-(p-Tolyl)proplonic acid Ibuprofen EP Impurity D (2-(p-Tolyl)propionic Acid) (2S)-2-(4-methylphenyl)propanoate IBUPROFEN IMP D IBUPROFEN IMPURITY D 4-METHYL-2-PHENYLPROPIONIC ACID alpha,4-Dimethylphenylacetic acid 97% (2R)-2-(4-Methylphenyl)propanoic acid ALPHA,4-DIMETHYLPHENYLACETIC ACID 2-(4-METHYLPHENYL)PROPANOIC ACID 2-(4-METHYLPHENYL)PROPIONIC ACID 2-(P-TOLYL)PROPIONIC ACID 2-(p-Methylphenyl)propionic acid a,4-Dimethylbenzeneacetic acid 2-(p-Tolyl)propionic acid,98% 2-p-Tolylpropanoic acid α,4-dimethylphenylacetic acid p-Methylhydratropic acid. 2-(4-tolyl)propanoic acid 2-(4-Tolyl)propionic acid Methylphenylpropinoic acid 2-p-Tolylpropanoic acid / 2-(4-Tolyl)propionic acid Ibuprofen EP Impurity D：Ibuprofen Impurity D (2RS)-2-(4-Methylphenyl)propanoic A 2-(4-MethyL Benzeneacetic acid, α,4-dimethyl- Ibuprofen Impurity 4（Ibuprofen EP Impurity D） p-Methyl isopropionic acid　 Ibuprofen Impurity DQ: What is Ibuprofen Impurity D Q: What is the CAS Number of Ibuprofen Impurity D Q: What is the storage condition of Ibuprofen Impurity D Q: What are the applications of Ibuprofen Impurity D 2-(4-Methylphenyl)propanoicaci (2RS)-2-(4-methylphenyl)propanoic acid 2- (p-toluene) propionic acid 2-(4-Methylphenyl)propanoic acid(MPPA) Loxoprofen sodium Impurity 2 α,4-Dimethylphenylacetic acid (2RS)-2-(4-METHYLPHENYL)PROPANOIC ACID 938-94-3 CH3C6H4CHCH3CO2H CARBOXYLIC ACID Building Blocks Carbonyl Compounds Carboxylic Acids C10 Organic Building Blocks Aromatic Propionic Acids Carboxylic Acids Phenyls & Phenyl-Het Carboxylic Acids