6-Azaindole-3-carboxaldehyde
- CAS No.
- 25957-65-7
- Chemical Name:
- 6-Azaindole-3-carboxaldehyde
- Synonyms
- 6-Azaindole-3-aldehyde;6-Azaindole-3-carbaldehyde;3-c]pyridine-3-carbaldehyde;6-Azazindole-3-carboxyaldehyde.;H-pyrrolo[2,3-c]pyridine-3-carbaldehyde;1H-Pyrrolo[2,3-c]pyridine-3-carboxaldehyde;1-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde (7CI)
- CBNumber:
- CB01216033
- Molecular Formula:
- C8H6N2O
- Molecular Weight:
- 146.15
- MDL Number:
- MFCD08272238
- MOL File:
- 25957-65-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | OR942291 | 250mg | $28 |
| 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | OR942291 | 1g | $39 |
| 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | OR942291 | 5g | $153 |
| 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | OR942291 | 10g | $293 |
| 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | OR942291 | 25g | $455 |
| More product size | |||
| Boiling point | 383.2±22.0 °C(Predicted) |
|---|---|
| Density | 1.368 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 13.16±0.40(Predicted) |
| Appearance | Off-white to gray Solid |
| InChI | InChI=1S/C8H6N2O/c11-5-6-3-10-8-4-9-2-1-7(6)8/h1-5,10H |
| InChIKey | IAMJYHYPXUQXGI-UHFFFAOYSA-N |
| SMILES | C1=NC=CC2C(C=O)=CNC1=2 |
| CAS DataBase Reference | 25957-65-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405 |
| HS Code | 2933998090 |
6-Azaindole-3-carboxaldehyde price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 250mg | $28 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 1g | $39 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 5g | $153 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 10g | $293 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 25g | $455 | 2026-06-04 | Buy |
6-Azaindole-3-carboxaldehyde Chemical Properties,Uses,Production
Uses
1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde is used in preparation of α,β-unsaturated ketone derivatives as microtubule inhibitors for treatment of tumor.
Synthesis
271-29-4
4885-02-3
25957-65-7
GENERAL STEPS: To a solution of 6-azaindole (0.400 g; 3.386 mmol) in a solvent mixture of 1,2-dichloroethane (10 mL) and nitromethane (10 mL), cooled to 0°C. A mixture of 1,1-dichlorodimethyl ether (1.544 mL; 16.92 mmol) and aluminum trichloride (1.500 g; 11.25 mmol) was slowly added dropwise under argon protection for a controlled time of 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of water and saturated sodium bicarbonate solution. The reaction mixture was extracted with a solvent mixture of dichloromethane and ethanol (9:1 v/v, 6 x 100 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford the crude product 1H-pyrrolo[2,3-c]pyridine-3-carboxaldehyde (0.295 g, 60% yield), which could be used in the subsequent reaction without further purification. Product characterization data: ESI/APCI(+) m/z: 147 ([M + H]+); ESI/APCI(-) m/z: 145 ([M - H]-). 1H NMR (DMSO-d6) δ: 10.01 (1H, s), 8.88 (1H, s), 8.50 (1H, s), 8.33 (1H, d), 8.00 (1H, d). d).
References
[1] Patent: WO2013/45516, 2013, A1. Location in patent: Page/Page column 200
6-Azaindole-3-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
View Lastest Price from 6-Azaindole-3-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-08 | 6-Azaindole-3-carboxaldehyde
25957-65-7
|
1kg | 98% | 10000kgS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-10 | 6-Azaindole-3-carboxaldehyde
25957-65-7
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 6-Azaindole-3-carboxaldehyde
25957-65-7
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 6-Azaindole-3-carboxaldehyde
25957-65-7
- $1.00
- 99%
- Career Henan Chemical Co
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