6-Azaindole-3-carboxaldehyde
- CAS No.
- 25957-65-7
- Chemical Name:
- 6-Azaindole-3-carboxaldehyde
- Synonyms
- 6-Azaindole-3-aldehyde;6-Azaindole-3-carbaldehyde;3-c]pyridine-3-carbaldehyde;6-Azazindole-3-carboxyaldehyde.;H-pyrrolo[2,3-c]pyridine-3-carbaldehyde;1H-Pyrrolo[2,3-c]pyridine-3-carboxaldehyde;1-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde (7CI)
- CBNumber:
- CB01216033
- Molecular Formula:
- C8H6N2O
- Molecular Weight:
- 146.15
- MDL Number:
- MFCD08272238
- MOL File:
- 25957-65-7.mol
- MSDS File:
- SDS
| Boiling point | 383.2±22.0 °C(Predicted) |
|---|---|
| Density | 1.368 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 13.16±0.40(Predicted) |
| Appearance | Off-white to gray Solid |
| InChI | InChI=1S/C8H6N2O/c11-5-6-3-10-8-4-9-2-1-7(6)8/h1-5,10H |
| InChIKey | IAMJYHYPXUQXGI-UHFFFAOYSA-N |
| SMILES | C1=NC=CC2C(C=O)=CNC1=2 |
| CAS DataBase Reference | 25957-65-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405 |
| HS Code | 2933998090 |
6-Azaindole-3-carboxaldehyde price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 250mg | $28 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 1g | $39 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 5g | $153 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 10g | $293 | 2026-06-04 | Buy |
| Apolloscientific | OR942291 | 1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde 97% | 25957-65-7 | 25g | $455 | 2026-06-04 | Buy |
6-Azaindole-3-carboxaldehyde Chemical Properties, Uses, Production
Uses
1H-Pyrrolo[2,3-c]pyridine-3-carbaldehyde is used in preparation of α,β-unsaturated ketone derivatives as microtubule inhibitors for treatment of tumor.
Synthesis
271-29-4
4885-02-3
25957-65-7
GENERAL STEPS: To a solution of 6-azaindole (0.400 g; 3.386 mmol) in a solvent mixture of 1,2-dichloroethane (10 mL) and nitromethane (10 mL), cooled to 0°C. A mixture of 1,1-dichlorodimethyl ether (1.544 mL; 16.92 mmol) and aluminum trichloride (1.500 g; 11.25 mmol) was slowly added dropwise under argon protection for a controlled time of 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of water and saturated sodium bicarbonate solution. The reaction mixture was extracted with a solvent mixture of dichloromethane and ethanol (9:1 v/v, 6 x 100 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford the crude product 1H-pyrrolo[2,3-c]pyridine-3-carboxaldehyde (0.295 g, 60% yield), which could be used in the subsequent reaction without further purification. Product characterization data: ESI/APCI(+) m/z: 147 ([M + H]+); ESI/APCI(-) m/z: 145 ([M - H]-). 1H NMR (DMSO-d6) δ: 10.01 (1H, s), 8.88 (1H, s), 8.50 (1H, s), 8.33 (1H, d), 8.00 (1H, d). d).
References
[1] Patent: WO2013/45516, 2013, A1. Location in patent: Page/Page column 200
6-Azaindole-3-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Ruide Famo Technology Co., Ltd | 13821803402 | RD_PHARM@163.com | China | 842 | 58 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4368 | 65 |
| Shijiazhuang suchen Chemical Technology Co. LTD | 186-33933494 18032288352 | 1130239@qq.com | China | 192 | 60 |
| Shanghai Litong Chemical Technology Co.,Ltd. | 13598610367 0373-7129549 | 2468833170@qq.com | China | 932 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 |
View Latest Price from 6-Azaindole-3-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-08 | 6-Azaindole-3-carboxaldehyde
25957-65-7
|
1kg | 98% | 10000kgS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-10 | 6-Azaindole-3-carboxaldehyde
25957-65-7
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 6-Azaindole-3-carboxaldehyde
25957-65-7
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 6-Azaindole-3-carboxaldehyde
25957-65-7
- $1.00
- 99%
- Career Henan Chemical Co
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