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EZ-LINK (TM) PFP-BIOTIN, 50 MG

EZ-LINK (TM) PFP-BIOTIN, 50 MG structure

CAS No.: 120550-35-8

Chemical Name:: EZ-LINK (TM) PFP-BIOTIN, 50 MG

Synonyms: Biotin-PFP;Biotin-opfp;Biotinyl-OPfp;CAS_120550-35-8;Biotin-PFP ester;(+)-Biotin-PFP-ester;EZ-LINK (TM) PFP-BIOTIN;EZ-LINK (TM) PFP-BIOTIN, 50 MG;Biotin pentafluorophenyl ester;Biotin-PFP Biotin pentafluorophenyl ester

CBNumber:: CB01477379

Molecular Formula:: C16H15F5N2O3S

Molecular Weight:: 410.36

MDL Number:: MFCD09952636

MOL File:: 120550-35-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-11 16:31:51

Product description	Number	Pack Size	Price
Biotin Pentafluorophenyl Ester >97.0%(HPLC)	B3173	50mg	$92
Biotin Pentafluorophenyl Ester >97.0%(HPLC)	B3173	250mg	$278
Biotin-PFP ester 98%	bp-21512	1G	$150
Biotin-PFP ester 98%	bp-21512	5G	$600
Biotin-PFP ester 98%	bp-21512	10G	$950
More product size

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EZ-LINK (TM) PFP-BIOTIN, 50 MG Properties

Melting point	190.0 to 194.0 °C
Boiling point	555.3±50.0 °C(Predicted)
Density	1.441
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form	powder to crystal
pka	13.89±0.40(Predicted)
color	White to Almost white
InChI	InChI=1S/C16H15F5N2O3S/c17-9-10(18)12(20)15(13(21)11(9)19)26-8(24)4-2-1-3-7-14-6(5-27-7)22-16(25)23-14/h6-7,14H,1-5H2,(H2,22,23,25)/t6-,7-,14-/m0/s1
InChIKey	DKTMDBQDSYQUEV-LEJLMFORSA-N
SMILES	C1(=O)N[C@]2([H])[C@H](CCCCC(OC3=C(F)C(F)=C(F)C(F)=C3F)=O)SC[C@]2([H])N1
CAS DataBase Reference	120550-35-8

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	NonHazardous
Precautionary statements	NonHazardous
HS Code	2934.99.9001

EZ-LINK (TM) PFP-BIOTIN, 50 MG price More Price(45)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B3173	Biotin Pentafluorophenyl Ester >97.0%(HPLC)	120550-35-8	50mg	$92	2026-04-30	Buy
TCI Chemical	B3173	Biotin Pentafluorophenyl Ester >97.0%(HPLC)	120550-35-8	250mg	$278	2026-04-30	Buy
BroadPharm	bp-21512	Biotin-PFP ester 98%	120550-35-8	1G	$150	2026-05-24	Buy
BroadPharm	bp-21512	Biotin-PFP ester 98%	120550-35-8	5G	$600	2026-05-24	Buy
BroadPharm	bp-21512	Biotin-PFP ester 98%	120550-35-8	10G	$950	2026-05-24	Buy

Product number	Packaging	Price	Buy
B3173	50mg	$92	Buy
B3173	250mg	$278	Buy
bp-21512	1G	$150	Buy
bp-21512	5G	$600	Buy
bp-21512	10G	$950	Buy

EZ-LINK (TM) PFP-BIOTIN, 50 MG Chemical Properties,Uses,Production

Description

Biotin-PFP ester will react with primary amino groups (-NH2) to form stable, irreversible amide bonds.

Uses

(+)-Biotin-PFP-ester is used to prepare melampomagnolide B as an antileukemic sesquiterpene.

Synthesis

771-61-9

58-85-5

120550-35-8

GENERAL STEPS: D-Biotin (2.95 g, 12.00 mmol) was dissolved in N,N-dimethylformamide (DMF, 10 mL) to which pentafluorophenol (Pfp-OH, 2.80 g, 15.20 mmol) was subsequently added. A DMF solution (15 mL) of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl, 5.70 g, 29.70 mmol) was slowly added dropwise to the above mixture over 30 min at 0 °C. After the dropwise addition, the reaction mixture was stirred overnight at room temperature under nitrogen atmosphere. Upon completion of the reaction, the product was washed with dichloromethane (DCM) to afford the target compound 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid perfluorophenyl ester in white powder form in 90% yield (4.50 g). The obtained product can be directly used in the subsequent reaction without further purification.1H NMR (D2O) data were as follows: δ 1.41-1.69 (m, 6H, CH2), 2.57 (d, 1H, CH2), 2.77-2.85 (m, 3H, CH2), 3.11-3.12 (m, 1H, CH), 4.14 (t, 1H, CH), 4.30 (t, 1H, CH), 6.37 (d, 2H, NH).

IC 50

Alkyl/ether

References

[1] Synthetic Communications, 1996, vol. 26, # 13, p. 2531 - 2547
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 7954 - 7955
[3] Russian Journal of Bioorganic Chemistry, 1994, vol. 20, # 8-9, p. 520 - 528
[4] Bioorganicheskaya Khimiya, 1994, vol. 20, # 8-9, p. 955 - 966
[5] Organic and biomolecular chemistry, 2003, vol. 1, # 6, p. 950 - 959

EZ-LINK (TM) PFP-BIOTIN, 50 MG Preparation Products And Raw materials

Raw materials

PENTAFLUOROPHENYL TRIFLUOROACETATE Pentafluorophenol D-Biotin N,N-Dimethylformamide n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride

Preparation Products

N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE D-BIOTINOL (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID Biotin-PEG6-NH-Boc

EZ-LINK (TM) PFP-BIOTIN, 50 MG Suppliers

Global( 121)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29816	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	10000	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9078	58

Supplier	Advantage
career henan chemical co	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58
TargetMol Chemicals Inc.	58
Wuhan Borenpharm Co., Ltd	58
ANHUI WITOP BIOTECH CO., LTD	58
Shaanxi Dideu Medichem Co. Ltd	58
Baoji Guokang Healthchem Co., Ltd.	58

View Lastest Price from EZ-LINK (TM) PFP-BIOTIN, 50 MG manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-11	Biotin-PFP ester 120550-35-8	US $0.00 / mg			10g	TargetMol Chemicals Inc.
2025-06-07	Biotin-PFP 120550-35-8	US $0.00 / mg	250mg	>95.00%	25g	Xian confluore Biological Technology Co., Ltd.
2021-07-13	EZ-LINK (TM) PFP-BIOTIN, 50 MG 120550-35-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Biotin-PFP ester
120550-35-8
US $0.00 / mg
TargetMol Chemicals Inc.

Biotin-PFP
120550-35-8
US $0.00 / mg
>95.00%
Xian confluore Biological Technology Co., Ltd.

EZ-LINK (TM) PFP-BIOTIN, 50 MG
120550-35-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

EZ-LINK (TM) PFP-BIOTIN, 50 MG Spectrum

EZ-LINK (TM) PFP-BIOTIN, 50 MG(120550-35-8)¹HNMR

120550-35-8(EZ-LINK (TM) PFP-BIOTIN, 50 MG)Related Search:

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DBCO-PEG4-biotin 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- (3aS,4S,6aR)-Hexahydro-2-oxo-N-(15-oxo-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl)-1H-thieno[3,4-d]imidazole-4-pentanamide

1of4

(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoicacid 2,3,4,5,6-pentafluorophenyl ester Biotin pentafluorophenyl ester EZ-LINK (TM) PFP-BIOTIN, 50 MG Biotin-PFP Biotin pentafluorophenyl ester Perfluorophenyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate CAS_120550-35-8 Biotin-opfp (2,3,4,5,6-pentafluorophenyl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate Biotin-PFP 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, 2,3,4,5,6-pentafluorophenyl ester, (3aS,4S,6aR)- (+)-Biotin-PFP-ester 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-,pentafluorophenyl ester, (3aS,4S,6aR)- EZ-LINK (TM) PFP-BIOTIN, 50 MG ISO 9001：2015 REACH Biotinyl-OPfp EZ-LINK (TM) PFP-BIOTIN Biotin-PFP ester 120550-35-8 C16H15F5N2O3S