EZ-LINK (TM) PFP-BIOTIN, 50 MG
- CAS No.
- 120550-35-8
- Chemical Name:
- EZ-LINK (TM) PFP-BIOTIN, 50 MG
- Synonyms
- Biotin-opfp;Biotin pentafluorophenyl ester;Biotin-PFP;Biotinyl-OPfp;CAS_120550-35-8;Biotin-PFP ester;(+)-Biotin-PFP-ester;EZ-LINK (TM) PFP-BIOTIN;EZ-LINK (TM) PFP-BIOTIN, 50 MG;Biotin-PFP Biotin pentafluorophenyl ester
- CBNumber:
- CB01477379
- Molecular Formula:
- C16H15F5N2O3S
- Molecular Weight:
- 410.36
- MDL Number:
- MFCD09952636
- MOL File:
- 120550-35-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 190.0 to 194.0 °C |
|---|---|
| Boiling point | 555.3±50.0 °C(Predicted) |
| Density | 1.441 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| form | powder to crystal |
| pka | 13.89±0.40(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C16H15F5N2O3S/c17-9-10(18)12(20)15(13(21)11(9)19)26-8(24)4-2-1-3-7-14-6(5-27-7)22-16(25)23-14/h6-7,14H,1-5H2,(H2,22,23,25)/t6-,7-,14-/m0/s1 |
| InChIKey | DKTMDBQDSYQUEV-LEJLMFORSA-N |
| SMILES | C1(=O)N[C@]2([H])[C@H](CCCCC(OC3=C(F)C(F)=C(F)C(F)=C3F)=O)SC[C@]2([H])N1 |
| CAS DataBase Reference | 120550-35-8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | NonHazardous |
| Precautionary statements | NonHazardous |
| HS Code | 2934.99.9001 |
EZ-LINK (TM) PFP-BIOTIN, 50 MG price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3173 | Biotin Pentafluorophenyl Ester >97.0%(HPLC) | 120550-35-8 | 50mg | $92 | 2026-04-30 | Buy |
| TCI Chemical | B3173 | Biotin Pentafluorophenyl Ester >97.0%(HPLC) | 120550-35-8 | 250mg | $278 | 2026-04-30 | Buy |
| Usbiological | 265975 | (+)-Biotin-PFP-ester Asreported | 120550-35-8 | 25mg | $333 | 2026-06-03 | Buy |
| Usbiological | 265975 | (+)-Biotin-PFP-ester Asreported | 120550-35-8 | 50mg | $456 | 2026-06-03 | Buy |
| Usbiological | 265975 | (+)-Biotin-PFP-ester Asreported | 120550-35-8 | 100mg | $611 | 2026-06-03 | Buy |
EZ-LINK (TM) PFP-BIOTIN, 50 MG Chemical Properties,Uses,Production
Description
Biotin-PFP ester will react with primary amino groups (-NH2) to form stable, irreversible amide bonds.
Uses
(+)-Biotin-PFP-ester is used to prepare melampomagnolide B as an antileukemic sesquiterpene.
Synthesis
771-61-9
58-85-5
120550-35-8
GENERAL STEPS: D-Biotin (2.95 g, 12.00 mmol) was dissolved in N,N-dimethylformamide (DMF, 10 mL) to which pentafluorophenol (Pfp-OH, 2.80 g, 15.20 mmol) was subsequently added. A DMF solution (15 mL) of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl, 5.70 g, 29.70 mmol) was slowly added dropwise to the above mixture over 30 min at 0 °C. After the dropwise addition, the reaction mixture was stirred overnight at room temperature under nitrogen atmosphere. Upon completion of the reaction, the product was washed with dichloromethane (DCM) to afford the target compound 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid perfluorophenyl ester in white powder form in 90% yield (4.50 g). The obtained product can be directly used in the subsequent reaction without further purification.1H NMR (D2O) data were as follows: δ 1.41-1.69 (m, 6H, CH2), 2.57 (d, 1H, CH2), 2.77-2.85 (m, 3H, CH2), 3.11-3.12 (m, 1H, CH), 4.14 (t, 1H, CH), 4.30 (t, 1H, CH), 6.37 (d, 2H, NH).
IC 50
Alkyl/ether
References
[1] Synthetic Communications, 1996, vol. 26, # 13, p. 2531 - 2547
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 7954 - 7955
[3] Russian Journal of Bioorganic Chemistry, 1994, vol. 20, # 8-9, p. 520 - 528
[4] Bioorganicheskaya Khimiya, 1994, vol. 20, # 8-9, p. 955 - 966
[5] Organic and biomolecular chemistry, 2003, vol. 1, # 6, p. 950 - 959
EZ-LINK (TM) PFP-BIOTIN, 50 MG Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 472 | 75 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Beijing Isomersyn Technology CO;LTD | 010-82954736 13391601435 | sales@isomersyn.com | China | 3294 | 57 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| ZhengZhou HuaWen Chemical Co.Ltd | 0370-2785118 17550508557 | 675141927@qq.com | China | 3201 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
View Lastest Price from EZ-LINK (TM) PFP-BIOTIN, 50 MG manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-04 | EZ-LINK (TM) PFP-BIOTIN, 50 MG
120550-35-8
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-05-11 | Biotin-PFP ester
120550-35-8
|
10g | TargetMol Chemicals Inc. | ||||
 |
2025-06-07 | Biotin-PFP
120550-35-8
|
250mg | >95.00% | 25g | Xian confluore Biological Technology Co., Ltd. |
-
- EZ-LINK (TM) PFP-BIOTIN, 50 MG
120550-35-8
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Biotin-PFP ester
120550-35-8
- $0.00
- TargetMol Chemicals Inc.
-
- Biotin-PFP
120550-35-8
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
