Biotin-PEG2-C4-Alkyne
- CAS No.
- 1011268-28-2
- Chemical Name:
- Biotin-PEG2-C4-Alkyne
- Synonyms
- Biotin-PEG2-C4-Alkyne;Biotin-PEG2-C4-Propargy;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-[2-[2-[2-[(1-oxo-5-hexyn-1-yl)amino]ethoxy]ethoxy]ethyl]-, (3aS,4S,6aR)-
- CBNumber:
- CB73062389
- Molecular Formula:
- C22H36N4O5S
- Molecular Weight:
- 468.61
- MDL Number:
- MFCD28505539
- MOL File:
- 1011268-28-2.mol
- MSDS File:
- SDS
Biotin-PEG2-C4-Alkyne price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 13038 | Alkynyl-biotin ≥95% | 1011268-28-2 | 1mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 13038 | Alkynyl-biotin ≥95% | 1011268-28-2 | 5mg | $402 | 2026-04-30 | Buy |
| Cayman Chemical | 13038 | Alkynyl-biotin ≥95% | 1011268-28-2 | 10mg | $702 | 2026-04-30 | Buy |
| Biosynth | LQB26828 | Alkynyl-biotin | 1011268-28-2 | 10mg | $851.7 | 2026-06-04 | Buy |
| Biosynth | LQB26828 | Alkynyl-biotin | 1011268-28-2 | 25mg | $1388.75 | 2026-06-04 | Buy |
Biotin-PEG2-C4-Alkyne Chemical Properties,Uses,Production
Description
Alkynyl-biotin is a form of biotin with a terminal alkyne group separated by two polyethylene glycol moieties. It is used to add biotin to other molecules bearing an azide group using a copper Cu(I)-catalyzed azide-alkyne cycloaddition reaction. Alkynyl-biotin has been used to add a biotin tag to a range of biochemicals, amino acids, proteins, and nucleotides that have been modified by the addition of an azide group. Alkynyl-biotin can also be used to capture sulfenic acid-modified proteins that have been tagged with the cell-permeable probe DAz-2 .
Uses
Biotin-PEG2-C4-alkyne is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG2-C4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] DANIEL B. MCCLATCHY, *. Pulsed Azidohomoalanine Labeling in Mammals (PALM) Detects Changes in Liver-Specific LKB1 Knockout Mice[J]. Journal of Proteome Research, 2015, 14 11: 4815-4822. DOI: 10.1021/acs.jproteome.5b00653
[2] PENG WU. A high-throughput-compatible assay to measure the degradation of endogenous Huntingtin proteins[J]. Acta Pharmacologica Sinica, 2016, 37 10: 1307-1314. DOI: 10.1038/aps.2016.31
[3] JESSICA ZAYAS. Strain Promoted Click Chemistry of 2- or 8-Azidopurine and 5-Azidopyrimidine Nucleosides and 8-Azidoadenosine Triphosphate with Cyclooctynes. Application to Living Cell Fluorescent Imaging[J]. Bioconjugate Chemistry Bioconjugate, 2015, 26 8: 1519-1532. DOI: 10.1021/acs.bioconjchem.5b00300
[4] STEPHEN E. LEONARD Kate S C Khalilah G Reddie. Mining the Thiol Proteome for Sulfenic Acid Modifications Reveals New Targets for Oxidation in Cells[J]. ACS Chemical Biology, 2009, 4 9: 783-799. DOI: 10.1021/cb900105q
Biotin-PEG2-C4-Alkyne Preparation Products And Raw materials
Raw materials
Preparation Products
Biotin-PEG2-C4-Alkyne Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1977 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26012 | 58 |
| Hangzhou Taorui Biotechnology Co., Ltd | QQ1259737804 15268198094 | sales@torreybio.com | China | 4128 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
View Lastest Price from Biotin-PEG2-C4-Alkyne manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | Biotin-PEG2-C4-alkyne
1011268-28-2
|
$337.00-2300.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | Biotin-PEG2-C4-alkyne
1011268-28-2
|
10mg | >95.00% | 10mg | Xian confluore Biological Technology Co., Ltd. |
-
- Biotin-PEG2-C4-alkyne
1011268-28-2
- $337.00-2300.00
- TargetMol Chemicals Inc.
-
- Biotin-PEG2-C4-alkyne
1011268-28-2
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
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