4-Bromo-3-fluorobenzoic acid ethyl ester
- CAS No.
- 1130165-74-0
- Chemical Name:
- 4-Bromo-3-fluorobenzoic acid ethyl ester
- Synonyms
- Ethyl 4-bromo-3-fluorobenzoat;4-Bromo-3-fluorobenzoic acid ethyl ester;Benzoic acid, 4-bromo-3-fluoro-, ethyl ester
- CBNumber:
- CB01484856
- Molecular Formula:
- C9H8BrFO2
- Molecular Weight:
- 247.06
- MDL Number:
- MFCD09751983
- MOL File:
- 1130165-74-0.mol
- MSDS File:
- SDS
| Boiling point | 285.4±25.0 °C(Predicted) |
|---|---|
| Density | 1.504±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | liquid |
| color | Clear, colourless |
| EPA Substance Registry System | Benzoic acid, 4-bromo-3-fluoro-, ethyl ester (1130165-74-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H317-H335-H401 |
| Precautionary statements | P501-P261-P273-P272-P270-P271-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P333+P313-P301+P312+P330-P304+P340+P312-P403+P233-P405 |
| TSCA | TSCA listed |
| HS Code | 2916399090 |
4-Bromo-3-fluorobenzoic acid ethyl ester price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC53348 | Ethyl 4-bromo-3-fluorobenzoate 99% | 1130165-74-0 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC53348 | Ethyl 4-bromo-3-fluorobenzoate 99% | 1130165-74-0 | 5g | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC53348 | Ethyl 4-bromo-3-fluorobenzoate 99% | 1130165-74-0 | 25g | $59 | 2026-06-04 | Buy |
| Activate Scientific | AS47685 | Ethyl 4-bromo-3-fluorobenzoate 99% | 1130165-74-0 | 5g | $22 | 2026-06-04 | Buy |
| Activate Scientific | AS47685 | Ethyl 4-bromo-3-fluorobenzoate 99% | 1130165-74-0 | 25g | $65 | 2026-06-04 | Buy |
4-Bromo-3-fluorobenzoic acid ethyl ester Chemical Properties, Uses, Production
Synthesis
64-17-5
153556-42-4
1130165-74-0
To a suspension of 4-bromo-3-fluorobenzoic acid (15.0 g) in anhydrous ethanol (230 mL) was slowly added concentrated sulfuric acid (8.0 mL). The reaction mixture was placed in a 60°C oil bath and stirred for 66 hours. After completion of the reaction, it was cooled to room temperature and the solvent was removed by rotary evaporator under reduced pressure. The residue was washed with 1 N sodium hydroxide solution (70 mL) and subsequently extracted with ethyl acetate (500 mL). The organic phase was washed sequentially with water (250 mL) and saturated saline (250 mL), dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Ethyl 4-bromo-3-fluorobenzoate was obtained as a light yellow solid (17.0 g, quantitative yield). Mass spectral analysis showed M/Z (M [79 Br] + H)+ = 247.
References
[1] Patent: EP2210891, 2010, A1. Location in patent: Page/Page column 17-18
[2] Journal of Medicinal Chemistry, 2009, vol. 52, # 6, p. 1540 - 1545
4-Bromo-3-fluorobenzoic acid ethyl ester Preparation Products And Raw materials
4-Bromo-3-fluorobenzoic acid ethyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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View Latest Price from 4-Bromo-3-fluorobenzoic acid ethyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-13 | 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
1130165-74-0
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
1130165-74-0
- $7.00
- 99%
- Career Henan Chemical Co
