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PROTAC SMARCA2/4-degrader-23

CAS No.
2568277-50-7
Chemical Name:
PROTAC SMARCA2/4-degrader-23
Synonyms
PROTAC SMARCA2/4-degrader-23
CBNumber:
CB014907652
Molecular Formula:
C52H64N12O6S
Molecular Weight:
985.21
MDL Number:
MOL File:
2568277-50-7.mol
Last updated:2025-04-17 18:22:24

PROTAC SMARCA2/4-degrader-23 Properties

Density 1.398±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 6.274±0.30(predicted)

PROTAC SMARCA2/4-degrader-23 Chemical Properties, Uses, Production

Uses

SMARCA2 degrader-15 (compound I-409) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC50s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment[1].

References

[1] Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.

PROTAC SMARCA2/4-degrader-23 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC SMARCA2/4-degrader-23 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
PROTAC SMARCA2/4-degrader-23 2568277-50-7