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METHYL OXALYL CHLORIDE

CAS No.
5781-53-3
Chemical Name:
METHYL OXALYL CHLORIDE
Synonyms
Methyl 2-chloro-2-oxoacetate;METHYL CHLOROOXOACETATE;Methyl (Chlorocarbonyl)formate;METHYL CHLOROGLYOXYLATE;MONO-METHYL OXALYL CHLORIDE;Kelex-103;orocarbonyL;Methyl Oxalyl Choride;METHYL OXALYL CHLORIDE;Methyleoxalyl chloride
CBNumber:
CB0177645
Molecular Formula:
C3H3ClO3
Molecular Weight:
122.51
MDL Number:
MFCD00000705
MOL File:
5781-53-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:13:05
Product description Number Pack Size Price
Methyl chlorooxoacetate 96% 151440 5g $57.7
Methyl chlorooxoacetate 96% 151440 10g $96.4
Methyl Chloroglyoxylate >98.0%(GC)(T) C1561 25g $110
Methyl Chloroglyoxylate >98.0%(GC)(T) C1561 250g $436
Methyl chlorooxoacetate 96% 151440 50g $315
More product size

METHYL OXALYL CHLORIDE Properties

Boiling point 118-120 °C (lit.)
Density 1.332 g/mL at 25 °C (lit.)
refractive index n20/D 1.419(lit.)
Flash point 116 °F
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly), Ethyl Acetate
form Liquid
color Clear
Odor Acrid
Water Solubility Miscible with water.
Sensitive Moisture Sensitive
BRN 1071541
Stability Hygroscopic
InChI 1S/C3H3ClO3/c1-7-3(6)2(4)5/h1H3
InChIKey ZXUQEPZWVQIOJE-UHFFFAOYSA-N
SMILES COC(=O)C(Cl)=O
CAS DataBase Reference 5781-53-3(CAS DataBase Reference)
FDA UNII 42Z6XG83RQ
EPA Substance Registry System Acetic acid, chlorooxo-, methyl ester (5781-53-3)
UNSPSC Code 12352101
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H226-H314-H335
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
target organs Respiratory system
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C,F
Risk Statements  34-37-10-36-14
Safety Statements  26-36/37/39-45-16
RIDADR  UN 2920 8/PG 2
WGK Germany  3
9-21
TSCA  TSCA listed
HazardClass  8
PackingGroup  II
HS Code  29171900
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1B
STOT SE 3
NFPA 704
2
3 0
W

METHYL OXALYL CHLORIDE price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 151440 Methyl chlorooxoacetate 96% 5781-53-3 5g $57.7 2025-07-31 Buy
Sigma-Aldrich 151440 Methyl chlorooxoacetate 96% 5781-53-3 10g $96.4 2025-07-31 Buy
TCI Chemical C1561 Methyl Chloroglyoxylate >98.0%(GC)(T) 5781-53-3 25g $110 2025-07-31 Buy
TCI Chemical C1561 Methyl Chloroglyoxylate >98.0%(GC)(T) 5781-53-3 250g $436 2025-07-31 Buy
Sigma-Aldrich 151440 Methyl chlorooxoacetate 96% 5781-53-3 50g $315 2025-07-31 Buy
Product number Packaging Price Buy
151440 5g $57.7 Buy
151440 10g $96.4 Buy
C1561 25g $110 Buy
C1561 250g $436 Buy
151440 50g $315 Buy

METHYL OXALYL CHLORIDE Chemical Properties,Uses,Production

Uses

Methyl oxalyl chloride is an important organic intermediate (building block) to synthetize substituted methyl oxalyl products. It can be used for regioselective synthesis of fused coumarins, cyclization to form substituted isoxazoles and heterocycles, intramolecular Wittig reactions, silyl enol ether acylation, and iron-mediated cleavage of C-C bonds.

Chemical Properties

CLEAR LIQUID

Uses

Methyl oxalyl chloride is used as a synthetic reagent. It serves as a reagent in the synthesis of fused coumarins, substituted isoxazoles and heterocycles. Further, it is used in intramolecular Wittig reactions, and iron-mediated cleavage of C-C bonds.

Uses

Reactant involved in:

  • Regioselective synthesis of fused coumarins
  • Cyclization to form substituted isoxazoles and heterocycles
  • Intramolecular Wittig reactions
  • Silyl enol ether acylation
  • Iron-mediated cleavage of C-C bonds

reaction suitability

reagent type: oxidant

67-56-1
79-37-8
5781-53-3
Synthesis of METHYL OXALYL CHLORIDE from Methanol and Oxalyl chloride
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Ningxia Jinhua Chemical Co.,Ltd
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ATK CHEMICAL COMPANY LIMITED
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Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58

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  • Feb 18,2020

View Lastest Price from METHYL OXALYL CHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHYL OXALYL CHLORIDE pictures 2026-01-29 METHYL OXALYL CHLORIDE
5781-53-3
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
METHYL OXALYL CHLORIDE pictures 2026-01-04 METHYL OXALYL CHLORIDE
5781-53-3
US $0.00-0.00 / kg 1kg 99.0%min 10000kg Hangzhou ICH Biofarm Co., Ltd
Methyl Oxalyl Choride pictures 2025-05-26 Methyl Oxalyl Choride
5781-53-3
US $6.00 / kg 1kg 0.99 10000 Hebei Fengjia New Material Co., Ltd
MONO-METHYL OXALYL CHLORIDE CHLOROGLYOXYLIC ACID METHYL ESTER METHYL CHLOROFORMYLFORMATE METHYL CHLOROGLYOXALATE METHYL CHLOROGLYOXYLATE METHYL CHLOROOXOACETATE METHYL OXALYL CHLORIDE Methyl Oxalyl Choride Methyl 2-chloro-2-oxoacetate Acetic acid,2-chloro-2-oxo-, Methyl ester Oxalyl chloride MonoMethyl ester Grass single Methyl chloride Methyl chlorooxoacetate 96% Acetic acid, chlorooxo-, methyl ester Methyl chloroglyoxylate for synthesis Methyleoxalyl chloride chlorogyloxylicacidmethylester chlorooxo-aceticacimethylester METHYL CHLOROOXOACETATE,96% Methyloxalylchloride,97% Methyl (Chlorocarbonyl)formate Oxalic acid monomethyl ester chloride Methyl chloroglyoxalate, Methyl oxalyl chloride, Monomethyl oxalyl chloride Methyl chloroglyoxalate, Methyl oxalyl chloride (Oxalic acid 1-methyl) chloride 2-Chloroglyoxylic acid methyl ester 2-Oxo-2-chloroacetic acid methyl ester Chlorooxoacetic acid methyl ester Oxochloroacetic acid methyl ester Methyl oxalyl chloride ,98% Methyl chlorooxoacetate ,97% Chloroglyoxylic Acid Methyl Ester Methyl Oxalyl Chloride orocarbonyL Methyl Chloroglyoxylate > Chloroglyoxylic Acid Methyl Ester,>98% Kelex-103 Foscarbidopa Impurity 9 Methyl oxalyl chloride 98% 5781-53-3 C3H3ClO3 ClCOCOOCH3 ACID CHLORIDE Synthetic Reagents Others Oxidation Organics