METHYL OXALYL CHLORIDE
- CAS No.
- 5781-53-3
- Chemical Name:
- METHYL OXALYL CHLORIDE
- Synonyms
- Methyl 2-chloro-2-oxoacetate;METHYL CHLOROOXOACETATE;Methyl (Chlorocarbonyl)formate;METHYL CHLOROGLYOXYLATE;MONO-METHYL OXALYL CHLORIDE;Kelex-103;orocarbonyL;Methyl Oxalyl Choride;METHYL OXALYL CHLORIDE;Methyleoxalyl chloride
- CBNumber:
- CB0177645
- Molecular Formula:
- C3H3ClO3
- Molecular Weight:
- 122.51
- MDL Number:
- MFCD00000705
- MOL File:
- 5781-53-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl chlorooxoacetate 96% | 151440 | 5g | $57.7 |
| Methyl chlorooxoacetate 96% | 151440 | 10g | $96.4 |
| Methyl Chloroglyoxylate >98.0%(GC)(T) | C1561 | 25g | $110 |
| Methyl Chloroglyoxylate >98.0%(GC)(T) | C1561 | 250g | $436 |
| Methyl chlorooxoacetate 96% | 151440 | 50g | $315 |
| More product size | |||
| Boiling point | 118-120 °C (lit.) |
|---|---|
| Density | 1.332 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 116 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate |
| form | Liquid |
| color | Clear |
| Odor | Acrid |
| Water Solubility | Miscible with water. |
| Sensitive | Moisture Sensitive |
| BRN | 1071541 |
| Stability | Hygroscopic |
| InChI | 1S/C3H3ClO3/c1-7-3(6)2(4)5/h1H3 |
| InChIKey | ZXUQEPZWVQIOJE-UHFFFAOYSA-N |
| SMILES | COC(=O)C(Cl)=O |
| CAS DataBase Reference | 5781-53-3(CAS DataBase Reference) |
| FDA UNII | 42Z6XG83RQ |
| EPA Substance Registry System | Acetic acid, chlorooxo-, methyl ester (5781-53-3) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H314-H335 | |||||||||
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C,F | |||||||||
| Risk Statements | 34-37-10-36-14 | |||||||||
| Safety Statements | 26-36/37/39-45-16 | |||||||||
| RIDADR | UN 2920 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 9-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29171900 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Dam. 1 Flam. Liq. 3 Skin Corr. 1B STOT SE 3 |
|||||||||
| NFPA 704 |
|
METHYL OXALYL CHLORIDE price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 151440 | Methyl chlorooxoacetate 96% | 5781-53-3 | 5g | $57.7 | 2025-07-31 | Buy |
| Sigma-Aldrich | 151440 | Methyl chlorooxoacetate 96% | 5781-53-3 | 10g | $96.4 | 2025-07-31 | Buy |
| TCI Chemical | C1561 | Methyl Chloroglyoxylate >98.0%(GC)(T) | 5781-53-3 | 25g | $110 | 2025-07-31 | Buy |
| TCI Chemical | C1561 | Methyl Chloroglyoxylate >98.0%(GC)(T) | 5781-53-3 | 250g | $436 | 2025-07-31 | Buy |
| Sigma-Aldrich | 151440 | Methyl chlorooxoacetate 96% | 5781-53-3 | 50g | $315 | 2025-07-31 | Buy |
METHYL OXALYL CHLORIDE Chemical Properties,Uses,Production
Uses
Methyl oxalyl chloride is an important organic intermediate (building block) to synthetize substituted methyl oxalyl products. It can be used for regioselective synthesis of fused coumarins, cyclization to form substituted isoxazoles and heterocycles, intramolecular Wittig reactions, silyl enol ether acylation, and iron-mediated cleavage of C-C bonds.
Chemical Properties
CLEAR LIQUID
Uses
Methyl oxalyl chloride is used as a synthetic reagent. It serves as a reagent in the synthesis of fused coumarins, substituted isoxazoles and heterocycles. Further, it is used in intramolecular Wittig reactions, and iron-mediated cleavage of C-C bonds.
Uses
Reactant involved in:
- Regioselective synthesis of fused coumarins
- Cyclization to form substituted isoxazoles and heterocycles
- Intramolecular Wittig reactions
- Silyl enol ether acylation
- Iron-mediated cleavage of C-C bonds
reaction suitability
reagent type: oxidant
METHYL OXALYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Ningxia Jinhua Chemical Co.,Ltd | +86-025-52279164 +8615996340606 | info@nxjhchem.com | China | 79 | 58 |
| Zhejiang Kinso Technology Co., LTD. | +86-571-56950601; +8619857958369 | sales@kinsopharma.com | China | 48 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21599 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Anhui Royal Chemical Co., Ltd. | +86-025-86655873 +8613962173137 | marketing@royal-chem.com | China | 200 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
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- Nov 20,2023
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View Lastest Price from METHYL OXALYL CHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-01-29 | METHYL OXALYL CHLORIDE
5781-53-3
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2026-01-04 | METHYL OXALYL CHLORIDE
5781-53-3
|
US $0.00-0.00 / kg | 1kg | 99.0%min | 10000kg | Hangzhou ICH Biofarm Co., Ltd | |
![]() |
2025-05-26 | Methyl Oxalyl Choride
5781-53-3
|
US $6.00 / kg | 1kg | 0.99 | 10000 | Hebei Fengjia New Material Co., Ltd |
-

- METHYL OXALYL CHLORIDE
5781-53-3
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- METHYL OXALYL CHLORIDE
5781-53-3
- US $0.00-0.00 / kg
- 99.0%min
- Hangzhou ICH Biofarm Co., Ltd
-

- Methyl Oxalyl Choride
5781-53-3
- US $6.00 / kg
- 0.99
- Hebei Fengjia New Material Co., Ltd










