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Boc-Leu-Gly-OH

CAS No.
32991-17-6
Chemical Name:
Boc-Leu-Gly-OH
Synonyms
Boc-Leu-Gly;Boc-Leu-Gly-OH;Boc-L-Leu-Gly-OH;N-Boc-L-leucyl-glycine;Boc-Leu-Gly-OH≥ 99% (TLC);(Tert-Butoxy)Carbonyl Leu-Gly-OH;tert-(Butyloxycarbonyl)leucylglycine;(tert-Butoxycarbonyl)-L-leucylglycine;N-(tert-Butoxycarbonyl)-L-leucylglycine;N-[(1,1-Dimethylethoxy)carbonyl]-L-leucylglycine
CBNumber:
CB0189132
Molecular Formula:
C13H24N2O5
Molecular Weight:
288.34
MDL Number:
MFCD00076954
MOL File:
32991-17-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:47:37

Boc-Leu-Gly-OH Properties

Melting point 162-165 °C
Boiling point 499.6±30.0 °C(Predicted)
Density 1.122±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
form Solid
pka 3.42±0.10(Predicted)
color White to off-white
optical activity Consistent with structure

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT

Boc-Leu-Gly-OH price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 264957 Boc-Leu-Gly-OH Asreported 32991-17-6 500mg $375 2026-06-03 Buy
Usbiological 264957 Boc-Leu-Gly-OH Asreported 32991-17-6 1g $578 2026-06-03 Buy
Usbiological 264957 Boc-Leu-Gly-OH Asreported 32991-17-6 2g $811 2026-06-03 Buy
ChemScene CS-0097840 (tert-Butoxycarbonyl)-L-leucylglycine ≥97% 32991-17-6 5g $40 2026-06-04 Buy
ChemScene CS-0097840 (tert-Butoxycarbonyl)-L-leucylglycine ≥97% 32991-17-6 10g $67 2026-06-04 Buy
Product number Packaging Price Buy
264957 500mg $375 Buy
264957 1g $578 Buy
264957 2g $811 Buy
CS-0097840 5g $40 Buy
CS-0097840 10g $67 Buy

Boc-Leu-Gly-OH Chemical Properties, Uses, Production

Chemical Properties

White powder

Uses

N-[N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl]-glycine is used to prepare aziridinedicarboxylic acid peptides as cysteine protease inhibitors. It is also used to prepare dipeptide monoester prodrugs of floxuridine with enhanced cancer cell growth inhibition.

Synthesis

Glycine,N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-, methyl ester

27610-07-7

BOC-LEU-GLY-OH

32991-17-6

General procedure for the synthesis of (S)-2-(2-((tert-butoxycarbonyl)amino)-4-methylpentanamido)acetic acid from (tert-butoxycarbonyl)-L-leucylglycine methyl ester: Compound 9a (2.6 g, 10 mmol) was dissolved in 50 mL of methanol, 1 M NaOH solution (30 mL) was added, and the reaction was stirred for 3 h at room temperature. Upon completion of the reaction, the solvent was removed by vacuum concentration and the pH of the residue was adjusted to 2-3 with 1 M HCl. Subsequently, the mixture was extracted three times with ethyl acetate (EtOAc). The organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4). After filtration, ethyl acetate was evaporated under reduced pressure to give compound 10a as a white solid in 92.4% yield.

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 11, p. 3055 - 3064
[2] Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2009, vol. 64, # 2, p. 237 - 244
[3] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 2, p. 887 - 895

Boc-Leu-Gly-OH Preparation Products And Raw materials

Global Suppliers ( 90)
Supplier Tel Email Country ProdList Advantage
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Syntechem Co.,Ltd info@syntechem.com China 12973 57
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Balmxy Pharmaceutical Co., Ltd 021-24206007 13764915196 sales@balmxy.com China 6967 55
NINGBO INNO PHARMCHEM CO.,LTD. 86-574-27787657 info@dearchem.com China 4607 58
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Zhengzhou Alfachem Co., Ltd. 0371-53765687 18937137882 3969243885@qq.com China 7731 55
Shanghai GL Peptide Ltd. +86-21-61263310 13764994101 fisherwang@glschina.com China 8058 55

View Latest Price from Boc-Leu-Gly-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BOC-LEU-GLY-OH pictures 2026-10-10 BOC-LEU-GLY-OH
32991-17-6
$1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
Boc-Leu-Gly-OH pictures 2026-09-30 Boc-Leu-Gly-OH
32991-17-6
1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
BOC-LEU-GLY-OH pictures 2025-04-04 BOC-LEU-GLY-OH
32991-17-6
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

Boc-Leu-Gly-OH Spectrum

N-[(1,1-Dimethylethoxy)carbonyl]-L-leucylglycine Boc-L-Leu-Gly-OH N-(tert-Butoxycarbonyl)-L-leucylglycine (S)-2-(2-((tert-Butoxycarbonyl)aMino)-4-MethylpentanaMido)acetic acid tert-(Butyloxycarbonyl)leucylglycine Boc-Leu-Gly-OH≥ 99% (TLC) (Tert-Butoxy)Carbonyl Leu-Gly-OH (tert-Butoxycarbonyl)-L-leucylglycine 2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methylpentanamido]acetic acid Glycine, N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl- 2-[[(2S)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]amino]acetic acid N-Boc-L-leucyl-glycine Boc-Leu-Gly Boc-Leu-Gly-OH 32991-17-6