ChemicalBook >> CAS DataBase List >>9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid

9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid

9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid structure

CAS No.: 209860-88-8

Chemical Name:: 9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid

Synonyms: AFP-172;209860-84-1;Taluprost acid;tafluprost acid;Tafluprost Impurity 9;TAFLUPROST (FREE ACID);Tafluprost Impurity DCP-1;Tafluoroprostaglandin impurity;Tafluprost Impurity Tafluprost acid;7-[2-(3,3-difluoro-4-phenoxybut-1-enyl)-3,5-dihydroxycyclopentyl]hept-5-enoic acid

CBNumber:: CB0224547

Molecular Formula:: C22H28F2O5

Molecular Weight:: 410.45

MDL Number:: MFCD08062149

MOL File:: 209860-88-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:47:41

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9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid Properties

Boiling point	575.9±50.0 °C(Predicted)
Density	1.271±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 30 mg/ml; DSMO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 3 mg/ml
form	Oil
pka	4.76±0.10(Predicted)
color	Colorless to light yellow
optical activity	[α]/D 17 to 22°, c =1.0 in methanol
InChIKey	KIQXRQVVYTYYAZ-VKVYFNERSA-N
SMILES	C(O)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/C(F)(F)COC1=CC=CC=C1
FDA UNII	WTV8EPZ396
UNSPSC Code	12352106
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H302-H360
Precautionary statements	P264-P270-P301+P312-P330-P501
WGK Germany	WGK 3
Storage Class	11 - Combustible Solids
Hazard Classifications	Repr. 2

9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	10005439	Tafluprost (free acid) ≥98%	209860-88-8	1mg	$127	2026-04-30	Buy
Cayman Chemical	10005439	Tafluprost (free acid) ≥98%	209860-88-8	5mg	$560	2026-04-30	Buy
Cayman Chemical	10005439	Tafluprost (free acid) ≥98%	209860-88-8	10mg	$995	2026-04-30	Buy
Cayman Chemical	10005439	Tafluprost (free acid) ≥98%	209860-88-8	25mg	$2172	2026-04-30	Buy
Biosynth	BT179039	Taluprost acid	209860-88-8	10mg	$162.2	2026-06-04	Buy

Product number	Packaging	Price	Buy
10005439	1mg	$127	Buy
10005439	5mg	$560	Buy
10005439	10mg	$995	Buy
10005439	25mg	$2172	Buy
BT179039	10mg	$162.2	Buy

9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid Chemical Properties, Uses, Production

Uses

Tafluprost Acid is a derivative of Tafluprost (T004820), a novel prostanoid used in the treatment of glaucoma and is the first prostanoid to be released in a preservative free-formula.

Biological Activity

Taflupost acid is the active metabolite of Tafluprost, a prostaglandin F2α agonist th at lowers intraocular pressure and is used in the treatment of glaucoma. Taflupost acid has high affinity and selectivity for the prostaglandin PGF2α (FP) receptor with a Ki of 0.4 nM.

IC 50

Human FP Receptor: 0.4 nM (Ki); Human FP Receptor: 0.53 nM (EC₅₀); EP3: 67 nM (IC₅₀)

9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid Preparation Products And Raw materials

Raw materials

Preparation Products

9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid Suppliers

Global Suppliers ( 104)

Supplier	Tel	Email	Country	ProdList	Advantage
Huigen Biotech (Shanghai) Co., Ltd.	13761582449; 13761582449	qingqing_claire@126.com	China	193	58
Wuhan Fortuna Chemical Co., Ltd	027-59207852 13308628970	buy@fortunachem.com	China	2690	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	5000	50
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
Shandong Boluoda Biological Technology Co., Ltd.	0531-68651502	2310993908@qq.com	China	3228	58
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9883	50
Shanghai Synchem Pharma Co., ltd	21-619849051-1 18521059765	synchempharma@aliyun.com	China	4988	55
Taizhou Ruixin Chemical Co., Ltd.	0576-89085261 15867635987	jasonhu09@163.com	China	439	50
BOC Sciences	16314854226	info@bocsci.com	United States	9909	65
Shanghai Changyan Chem & Tech Co., Ltd.	021-20242659 18930833303	sales@changyanchem.cn	China	4998	55

Supplier	Advantage
Huigen Biotech (Shanghai) Co., Ltd.	58
Wuhan Fortuna Chemical Co., Ltd	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
Quality Control Solutions Ltd.	56
Shandong Boluoda Biological Technology Co., Ltd.	58
Shanghai Kewel Chemical Co., Ltd.	50
Shanghai Synchem Pharma Co., ltd	55
Taizhou Ruixin Chemical Co., Ltd.	50
BOC Sciences	65
Shanghai Changyan Chem & Tech Co., Ltd.	55

View Latest Price from 9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-15	Tafluprost acid 209860-88-8	$417.00-3270.00			10g	TargetMol Chemicals Inc.
2025-12-24	9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID 209860-88-8		1KG	99.0%	1000 tons	Shaanxi Dideu Medichem Co. Ltd
2019-07-10	9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID 209860-88-8	$7.00	1KG	99%	100KG	Career Henan Chemical Co

Tafluprost acid
209860-88-8
$417.00-3270.00
TargetMol Chemicals Inc.

9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
209860-88-8
$0.10
99.0%
Shaanxi Dideu Medichem Co. Ltd

9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
209860-88-8
$7.00
99%
Career Henan Chemical Co

209860-88-8 (9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid) Related Search:

15-Keto latanoprost Tafluprost Impurity 7 Latanoprost Tris(triethylsilyl) Ether NCX 116 (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid

Latanoprost Lactone Diol Latanoprost acid 7-[(1R,2S)-2-[(1E,3S,5S)-3-Hydroxy-5-Methyl-1-nonenyl]-5-oxo-3-cyclopenten-1-yl]-2-heptenoic Acid 16-(3-chlorophenoxy)-17,18,19,20-tetranorprostaglandin F2 alpha (+)-5-trans Cloprostenol

(+)-15(S)-CLOPROSTENOL 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5E)-rel- Tafluprost 9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid

1of3

AFP-172 Tafluprost Impurity Tafluprost acid Tafluprost Impurity 9 TAFLUPROST (FREE ACID) tafluprost acid 7-[2-(3,3-difluoro-4-phenoxybut-1-enyl)-3,5-dihydroxycyclopentyl]hept-5-enoic acid 209860-84-1 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5Z)- (Z)-7-((1R,2R,3R,5S)-2-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoic acid Tafluoroprostaglandin impurity Tafluprost Impurity DCP-1 Taluprost acid 9alpha,11alpha-Dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5z,13e-dien-1-oic acid 209860-88-8 209860-84-1