ChemicalBook >> CAS DataBase List >>(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID structure

CAS No.: 766536-21-4

Chemical Name:: (R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID

Synonyms: PF-356231;PF 00356231;PF 356231, MMP-12 inhibitor;(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID;Benzenepropanoic acid, β-[[[4-[4-(4-pyridinyl)phenyl]-2-thienyl]carbonyl]amino]-, (βR)-;BENZENEPROPANOIC ACID, B-[[[4-[4-(4-PYRIDINYL)PHENYL]-2-THIENYL]CARBONYL]AMINO]-, (BR)-

CBNumber:: CB02454094

Molecular Formula:: C25H20N2O3S

Molecular Weight:: 428.5

MDL Number:: MFCD10565940

MOL File:: 766536-21-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 08:51:06

Product description	Number	Pack Size	Price
PF 00356231 98%	Axon1181	5mg	$154
PF 00356231 98%	Axon1181	25mg	$616
PF-00356231 98%	A1365994	5mg	$478
PF-00356231 98%	A1365994	25mg	$1079
(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID 98%	AA00GALU	5mg	$233

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(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID Properties

Boiling point	673.553±55.00 °C(Press: 760.00 Torr)(predicted)
Density	1.290±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
form	Yellow solid.
pka	4.153±0.10(predicted)

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Axon Medchem	Axon1181	PF 00356231 98%		5mg	$154	2026-05-19	Buy
Axon Medchem	Axon1181	PF 00356231 98%		25mg	$616	2026-05-19	Buy
Ambeed	A1365994	PF-00356231 98%	766536-21-4	5mg	$478	2026-06-05	Buy
Ambeed	A1365994	PF-00356231 98%	766536-21-4	25mg	$1079	2026-06-05	Buy
aablocks	AA00GALU	(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID 98%	766536-21-4	5mg	$233	2026-05-28	Buy

Product number	Packaging	Price	Buy
Axon1181	5mg	$154	Buy
Axon1181	25mg	$616	Buy
A1365994	5mg	$478	Buy
A1365994	25mg	$1079	Buy
AA00GALU	5mg	$233	Buy

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID Chemical Properties,Uses,Production

Uses

PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively[1].

References

[1] Morales R, et al. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76. DOI:10.1016/j.jmb.2004.06.039

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID Suppliers

Global( 27)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific		tp@aladdinsci.com	United States	50108	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	4993	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	11975	58

Supplier	Advantage
Aladdin Scientific	58
BOC Sciences	65
Shanghai EFE Biological Technology Co., Ltd.	58
Jinan Jiuli Biotechnology Co. , Ltd.	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID Spectrum

(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID(766536-21-4)¹HNMR

766536-21-4((R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID)Related Search:

MMP-2/MMP-9 INHIBITOR IV ISOBAVACHALCONE MCA-LYS-PRO-LEU-GLY-LEU-DAP(DNP)-ALA-ARG-NH2 Doxycycline hyclate MCA-PRO-LEU-ALA-NVA-DAP(DNP)-ALA-ARG-NH2

CL 82198 HYDROCHLORIDE Ilomastat AcetaMide, N-hydroxy-2-[[(4-Methoxyphenyl)sulfonyl](2-Methylpropyl)aMino]- (R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID

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(R)-3-PHENYL-3-([4-(4-PYRIDIN-4-YL-PHENYL)-THIOPHENE-2-CARBONYL]-AMINO)-PROPIONIC ACID BENZENEPROPANOIC ACID, B-[[[4-[4-(4-PYRIDINYL)PHENYL]-2-THIENYL]CARBONYL]AMINO]-, (BR)- PF 00356231 PF-356231 Benzenepropanoic acid, β-[[[4-[4-(4-pyridinyl)phenyl]-2-thienyl]carbonyl]amino]-, (βR)- PF 356231, MMP-12 inhibitor 766536-21-4