MMP-2/MMP-9 INHIBITOR IV
- CAS No.
- 292605-14-2
- Chemical Name:
- MMP-2/MMP-9 INHIBITOR IV
- Synonyms
- CS-860;SB-3CT;SB−SB-3CT (SB 3CT;SB-3CT, 10 mM in DMSO;MMP-2/MMP-9 INHIBITOR IV;MMP-2/MMP-9 INHIBITITOR IV;SB-3CT, MMP-2 and MMP-9 inhibitor;[[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane;2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane
- CBNumber:
- CB9223336
- Molecular Formula:
- C15H14O3S2
- Molecular Weight:
- 306.4
- MDL Number:
- MFCD09836266
- MOL File:
- 292605-14-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| SB?3CT ≥98% (HPLC), powder | S1326 | 5mg | $390 |
| MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem | 444274 | 500μg | $202 |
| SB-3CT | B5630 | 25MG | $209 |
| SB-3CT | B5630 | 100MG | $618 |
| SB-3CT ≥95% | 16337 | 500μg | $37 |
| More product size | |||
| Melting point | 92-96°C |
|---|---|
| Boiling point | 501.4±46.0 °C(Predicted) |
| Density | 1.329±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: >20mg/mL |
| form | powder |
| color | white to off-white |
| InChI | 1S/C15H14O3S2/c16-20(17,11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9,14H,10-11H2 |
| InChIKey | LSONWRHLFZYHIN-UHFFFAOYSA-N |
| SMILES | O=S(=O)(CC1CS1)c2ccc(Oc3ccccc3)cc2 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
MMP-2/MMP-9 INHIBITOR IV price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S1326 | SB?3CT ≥98% (HPLC), powder | 292605-14-2 | 5mg | $390 | 2026-03-19 | Buy |
| Sigma-Aldrich | 444274 | MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem | 292605-14-2 | 500μg | $202 | 2026-03-19 | Buy |
| TCI Chemical | B5630 | SB-3CT | 292605-14-2 | 25MG | $209 | 2026-03-19 | Buy |
| TCI Chemical | B5630 | SB-3CT | 292605-14-2 | 100MG | $618 | 2026-03-19 | Buy |
| Cayman Chemical | 16337 | SB-3CT ≥95% | 292605-14-2 | 500μg | $37 | 2024-03-01 | Buy |
MMP-2/MMP-9 INHIBITOR IV Chemical Properties,Uses,Production
Uses
SB 3CT is a selective and potent gelatinase inhibitor which may be used for the treatment of brain metastasis.
Uses
SB3CT has been used as irreversible inhibitor of matrix metallopeptidase 9 (MMP9) in cell cultures to exclude reciprocal regulation.
Definition
ChEBI: 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane is an aromatic ether.
Biochem/physiol Actions
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. In particular, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. SB-3CT exhibits a covalent mechanism based behavior in inhibition of MMP-2 and MMP-9. This inhibitor appears to have similarity to TIMP-1 and TIMP-2 in the slow-binding component of inhibition. SB-3CT has been shown to directly bind to the zinc in the catalytic site of MMP-2. SB-3CT does not affect the activities of MMP-1 (Ki = 206 μM) MMP-3 (Ki = 15 μM), or MMP-7 (Ki = 96 μM).
in vivo
SB-3CT (i.p.; 50 mg/kg; every other day; five weeks) inhibits intraosseous growth of human PC3 cells within the marrow of human fetal femur fragments previously implanted in SCID mice[3].
| Animal Model: | Five-week-old male C.B.-17.SCID mice[3] |
| Dosage: | 50 mg/kg |
| Administration: | IP; every other day; five weeks |
| Result: | Inhibited intraosseous growth of human PC3 cells within the marrow of human fetal femur fragments previously implanted in SCID mice. |
IC 50
MMP-2: 13.9 nM (Ki); MMP-9: 600 nM (Ki)
storage
Store at -20°C
MMP-2/MMP-9 INHIBITOR IV Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from MMP-2/MMP-9 INHIBITOR IV manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | SB-3CT
292605-14-2
|
US $41.00-162.00 / mg | 98.00% | 10g | TargetMol Chemicals Inc. | ||
![2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/185d93ab-5f96-40b1-998e-81889bf5adea.png) |
2020-01-02 | 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane
292605-14-2
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
-
- SB-3CT
292605-14-2
- US $41.00-162.00 / mg
- 98.00%
- TargetMol Chemicals Inc.
-
- 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane
292605-14-2
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co
