2-Morpholinoethanol
- CAS No.
- 622-40-2
- Chemical Name:
- 2-Morpholinoethanol
- Synonyms
- 2-Morpholinoethan-1-ol;4-MORPHOLINEETHANOL;2-MORPHOLIN-4-YL-ETHANOL;4-(2-HYDROXYETHYL)MORPHOLINE;N-(2-HYDROXYETHYL)MORPHOLINE;NSC 1946;AKOS MSC-0730;MORPHOLINOETHANOL;AKOS BBS-00004369;Morpholine ethanol
- CBNumber:
- CB0304252
- Molecular Formula:
- C6H13NO2
- Molecular Weight:
- 131.17
- MDL Number:
- MFCD00006180
- MOL File:
- 622-40-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -1 °C |
|---|---|
| Boiling point | 227 °C757 mm Hg(lit.) |
| Density | 1.083 g/mL at 25 °C(lit.) |
| vapor pressure | 2.44-7Pa at 20-25℃ |
| refractive index |
n |
| Flash point | 211 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Liquid |
| pka | 14.88±0.10(Predicted) |
| color | Clear colorless to yellow |
| PH | 10.7 (100g/l, H2O, 20℃) |
| explosive limit | 1.5-9.8%(V) |
| Water Solubility | miscible |
| BRN | 104375 |
| Henry's Law Constant | 1.4×103 mol/(m3Pa) at 25℃, Du et al. (2017) |
| InChI | 1S/C6H13NO2/c8-4-1-7-2-5-9-6-3-7/h8H,1-6H2 |
| InChIKey | KKFDCBRMNNSAAW-UHFFFAOYSA-N |
| SMILES | OCCN1CCOCC1 |
| LogP | -1.32 at 25℃ |
| CAS DataBase Reference | 622-40-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | LY5IL94D3K |
| NIST Chemistry Reference | 4-Morpholineethanol(622-40-2) |
| EPA Substance Registry System | 4-Morpholineethanol (622-40-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | QE3510000 | |||||||||
| F | 10-23 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2-Morpholinoethanol price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H28203 | 4-(2-Hydroxyethyl)morpholine ReagentPlus , 99% | 622-40-2 | 5g | $48.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | H28203 | 4-(2-Hydroxyethyl)morpholine ReagentPlus , 99% | 622-40-2 | 100g | $54.7 | 2026-04-30 | Buy |
| TCI Chemical | H0244 | 4-(2-Hydroxyethyl)morpholine >99.0%(GC) | 622-40-2 | 25mL | $21 | 2026-04-30 | Buy |
| TCI Chemical | H0244 | 4-(2-Hydroxyethyl)morpholine >99.0%(GC) | 622-40-2 | 100mL | $31 | 2026-04-30 | Buy |
| TRC | TRC-M723750-5G | 4-Morpholineethanol | 622-40-2 | 5g | $70 | 2026-06-03 | Buy |
2-Morpholinoethanol Chemical Properties, Uses, Production
Chemical Properties
2-Morpholinoethanol is a transparent colorless to yellow liquid. It is used as an organic chemical synthesis intermediate.
Uses
4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary cu lture/DNA.
Definition
ChEBI: 2-Morpholinoethanol is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group. It is a primary alcohol, a tertiary amino compound and a member of morpholines.
Synthesis Reference(s)
The Journal of Organic Chemistry, 52, p. 467, 1987 DOI: 10.1021/jo00379a035
Flammability and Explosibility
Non flammable
References
[1] Journal of the Indian Chemical Society, 1989, vol. 66, # 5, p. 316 - 318
[2] Patent: WO2014/12360, 2014, A1. Location in patent: Paragraph 00498
[3] Patent: US2015/87639, 2015, A1. Location in patent: Paragraph 0849; 0850
[4] Patent: TWI607995, 2017, B. Location in patent: Page/Page column 180
[5] Journal of Organic Chemistry, 2018, vol. 83, # 24, p. 15333 - 15346
2-Morpholinoethanol Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Juxido New Materials Co., Ltd | 13880299455 | 13880299455@163.com | China | 23 | 58 |
| Ningbo Hua Tuo Chemical Co., Ltd. | +86-0574-88237971 +86-15267895909 | mia@sinotopchem.com | China | 61 | 58 |
| Shandong Jiapeng New Materials Co. LTD | 0533-13355330258 13355330258 | sdjpxcl@163.com | China | 127 | 58 |
| Yangzhou Princechem Co.,Ltd | 18921928333 | david@princechem.com | China | 498 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
View Latest Price from 2-Morpholinoethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 2-Morpholinoethanol
622-40-2
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-06-20 | 2-Morpholinoethanol
622-40-2
|
1kg | 99% | 100tons | Hebei Yanxi Chemical Co., Ltd. | ||
 |
2025-05-26 | 2-Morpholinoethanol
622-40-2
|
$7.00 | 1kg | 0.99 | 10000 | Hebei Fengjia New Material Co., Ltd |
-
- 2-Morpholinoethanol
622-40-2
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2-Morpholinoethanol
622-40-2
- 99%
- Hebei Yanxi Chemical Co., Ltd.
-
- 2-Morpholinoethanol
622-40-2
- $7.00
- 0.99
- Hebei Fengjia New Material Co., Ltd
