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CU CPT 4a

CU CPT 4a structure

CAS No.: 1279713-77-7

Chemical Name:: CU CPT 4a

Synonyms: TLR3-IN-1;CU CPT 4a;TLR3-IN-1, 10 mM in DMSO;(3-Chloro-6-fluorobenzo[b]thiophene-2-carbonyl)-D-phenylalanine;N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine;D-Phenylalanine, N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-;TLR3/dsRNA complex,inhibit,CU-CPT 4a,TNF-α,protein-RNA interaction,IL-1β,TLR-3-IN-1,Inhibitor,TLR3 IN 1,TLR3IN1,Toll-like Receptor (TLR)

CBNumber:: CB03310333

Molecular Formula:: C18H13ClFNO3S

Molecular Weight:: 377.82

MDL Number:

MOL File:: 1279713-77-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-14 16:49:18

Product description	Number	Pack Size	Price
CU-CPT4a ≥98%	30951	500μg	$75
CU-CPT4a ≥98%	30951	1mg	$143
CU-CPT4a ≥98%	30951	5mg	$516
TLR3/dsRNA Complex Inhibitor (CU CPT 4a, Toll-Like Receptor 3/Double Strand RNA Complex Inhibitor)	217837	10mg	$566
CU CPT 4a	EBC71377	1mg	$250

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CU CPT 4a Properties

storage temp.	Store at 4°C
solubility	<37.78mg/ml in DMSO
form	solid
color	White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

CU CPT 4a price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	30951	CU-CPT4a ≥98%	1279713-77-7	500μg	$75	2026-04-30	Buy
Cayman Chemical	30951	CU-CPT4a ≥98%	1279713-77-7	1mg	$143	2026-04-30	Buy
Cayman Chemical	30951	CU-CPT4a ≥98%	1279713-77-7	5mg	$516	2026-04-30	Buy
Usbiological	217837	TLR3/dsRNA Complex Inhibitor (CU CPT 4a, Toll-Like Receptor 3/Double Strand RNA Complex Inhibitor)	1279713-77-7	10mg	$566	2026-06-03	Buy
Biosynth	EBC71377	CU CPT 4a	1279713-77-7	1mg	$250	2026-06-04	Buy

Product number	Packaging	Price	Buy
30951	500μg	$75	Buy
30951	1mg	$143	Buy
30951	5mg	$516	Buy
217837	10mg	$566	Buy
EBC71377	1mg	$250	Buy

CU CPT 4a Chemical Properties,Uses,Production

Uses

CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. CU-CPT 4a represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β[1].

Biological Activity

cu cpt 4a is a selective tlr3 inhibitor with ic50 of 3.44 μm in raw 264.7 cells. it can inhibit tlr3/dsrna complex-mediated downstream signaling pathways and inhibit the production of tnf-α and il-1β in whole cells. it reduces the mortality of crypt cells in mice and reduces gastrointestinal syndrome.[1]. cheng k, wang x, yin h. small-molecule inhibitors of the tlr3/dsrna complex. journal of the american chemical society, 2011, 133(11): 3764-3767.[2]. blockade of tlr3 protects mice from lethal radiation-induced gastrointestinal syndrome. nature communications, 2014, 5.

IC 50

TLR3: 3.44 μM (IC₅₀, in RAW 264.7 cells)

storage

Store at +4°C

References

[1] Yibo Wang, et al. Small-Molecule Modulators of Toll-like Receptors. Acc Chem Res. 2020 May 19;53(5):1046-1055. DOI:10.1021/acs.accounts.9b00631

CU CPT 4a Preparation Products And Raw materials

Raw materials

D-Phenylalanine

Preparation Products

CU CPT 4a Suppliers

Global( 53)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
Soochow Chirally Material Science and Technology Co.,Ltd	+86-51266834346 +86-17751128648	sales@krl-tech.com	China	1050	58
Shanghai Chenchu Chemical Co.,ltd.	13651748127	2684615189@qq.com	China	256	58
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4773	55
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3493	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60

Supplier	Advantage
TargetMol Chemicals Inc.	58
BOC Sciences	58
Aladdin Scientific	58
Soochow Chirally Material Science and Technology Co.,Ltd	58
Shanghai Chenchu Chemical Co.,ltd.	58
Guangzhou Isun Pharmaceutical Co., Ltd	55
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Bide Pharmatech Ltd.	60
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60

View Lastest Price from CU CPT 4a manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-13	TLR3-IN-1 1279713-77-7	$46.00-187.00		98.56%	10g	TargetMol Chemicals Inc.

TLR3-IN-1
1279713-77-7
$46.00-187.00
98.56%
TargetMol Chemicals Inc.

CU CPT 4a Spectrum

CU CPT 4a(1279713-77-7)¹HNMR

1279713-77-7(CU CPT 4a)Related Search:

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CU CPT 4a N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine D-Phenylalanine, N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]- TLR3-IN-1 TLR3/dsRNA complex,inhibit,CU-CPT 4a,TNF-α,protein-RNA interaction,IL-1β,TLR-3-IN-1,Inhibitor,TLR3 IN 1,TLR3IN1,Toll-like Receptor (TLR) (3-Chloro-6-fluorobenzo[b]thiophene-2-carbonyl)-D-phenylalanine TLR3-IN-1, 10 mM in DMSO 1279713-77-7