ChemicalBook >> CAS DataBase List >>Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-
Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-
- CAS No.
- 2471982-20-2
- Chemical Name:
- Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-
- Synonyms
- CU-115, 10 mM in DMSO;Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-
- CBNumber:
- CB48376376
- Molecular Formula:
- C21H11F7INO2
- Molecular Weight:
- 569.21
- MDL Number:
- MOL File:
- 2471982-20-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
| Product description | Number | Pack Size | Price |
| CU-115 ≥98% | 29815 | 1mg | $129 |
| CU-115 ≥98% | 29815 | 5mg | $415 |
| CU-115 ≥98% | 29815 | 10mg | $763 |
| CU-115 | WYD98220 | 5mg | $747.1 |
| CU-115 | WYD98220 | 10mg | $1195.5 |
| Boiling point | 427.3±45.0 °C(Predicted) |
|---|---|
| Density | 1.713±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 10mg/mL,DMSO: 10mg/mL,DMSO:PBS (pH 7.2) (1:5): 0.15mg/mL,Ethanol: 0.25mg/mL |
| form | A crystalline solid |
| pka | 11.28±0.70(Predicted) |
| color | White to off-white |
Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29815 | CU-115 ≥98% | 2471982-20-2 | 1mg | $129 | 2026-04-30 | Buy |
| Cayman Chemical | 29815 | CU-115 ≥98% | 2471982-20-2 | 5mg | $415 | 2026-04-30 | Buy |
| Cayman Chemical | 29815 | CU-115 ≥98% | 2471982-20-2 | 10mg | $763 | 2026-04-30 | Buy |
| Biosynth | WYD98220 | CU-115 | 2471982-20-2 | 5mg | $747.1 | 2026-06-05 | Buy |
| Biosynth | WYD98220 | CU-115 | 2471982-20-2 | 10mg | $1195.5 | 2026-06-05 | Buy |
Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo- Chemical Properties,Uses,Production
Uses
CU-115 is a potent TLR8 antagonist (IC50=1.04 μM), and shows selective for TLR8 over TLR7 (IC50=>50 μM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cells[1].
IC 50
TLR8: 1.04 μM (IC50); TLR7: 50 μM (IC50)
References
[1] Rosaura Padilla-Salinas, et al. Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors 7 and 8. J Med Chem. 2019 Nov 27;62(22):10221-10244. DOI:10.1021/acs.jmedchem.9b01201
Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo- Preparation Products And Raw materials
Raw materials
Preparation Products
Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo- Suppliers
Global( 24)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9811 | 55 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27602 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
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2471982-20-2(Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-)Related Search:
Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-
CU-115, 10 mM in DMSO
2471982-20-2
C21H11F7INO2





