ChemicalBook >> CAS DataBase List >>4-NITROPHENYL TRIFLUOROACETATE
4-NITROPHENYL TRIFLUOROACETATE
- CAS No.
- 658-78-6
- Chemical Name:
- 4-NITROPHENYL TRIFLUOROACETATE
- Synonyms
- TFAONP;Trifluoro-Ac;SAKAKI BARA'S REAGENT;4-Nitrophenyltrifluoracetat;p-Nitrophenyl trifuoroacetate;P-NITROPHENYL TRIFLUOROACETATE;4-NITROPHENYL TRIFLUOROACETATE;NITROPHENYLTRIFLUOROACETATE(4-);4-Nitrophenyltrifluoroacetate99%;4-Nitrophenyl trifluoroacetate 99%
- CBNumber:
- CB0332651
- Molecular Formula:
- C8H4F3NO4
- Molecular Weight:
- 235.12
- MDL Number:
- MFCD00007324
- MOL File:
- 658-78-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 17:39:33
| Melting point | 35-39 °C (lit.) |
|---|---|
| Boiling point | 120 °C/12 mmHg (lit.) |
| Density | 1.5675 (estimate) |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | almost transparency in Methanol |
| form | powder to lump to clear liquid |
| color | White or Colorless to Yellow |
| BRN | 658785 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C8H4F3NO4/c9-8(10,11)7(13)16-6-3-1-5(2-4-6)12(14)15/h1-4H |
| InChIKey | JFOIBTLTZWOAIC-UHFFFAOYSA-N |
| SMILES | C(OC1=CC=C([N+]([O-])=O)C=C1)(=O)C(F)(F)F |
| CAS DataBase Reference | 658-78-6(CAS DataBase Reference) |
| FDA UNII | H23CZQ62HC |
| EPA Substance Registry System | Acetic acid, trifluoro-, 4-nitrophenyl ester (658-78-6) |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P304+P340-P405-P501a-P261-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 21 | |||||||||
| Hazard Note | Harmful/Irritant/Keep Cold | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159000 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-NITROPHENYL TRIFLUOROACETATE price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N22657 | 4-Nitrophenyl trifluoroacetate 99% | 658-78-6 | 25g | $54 | 2023-06-20 | Buy |
| TCI Chemical | T0681 | 4-Nitrophenyl Trifluoroacetate >98.0%(GC) | 658-78-6 | 5g | $26 | 2026-04-30 | Buy |
| TCI Chemical | T0681 | 4-Nitrophenyl Trifluoroacetate >98.0%(GC) | 658-78-6 | 25g | $76 | 2026-04-30 | Buy |
| Usbiological | 233453 | 4-Nitrophenyl trifluoroacetate 99+% (HPLC) ≥99%(HPLC) | 5g | $156 | 2026-06-03 | Buy | |
| Usbiological | 233453 | 4-Nitrophenyl trifluoroacetate 99+% (HPLC) ≥99%(HPLC) | 25g | $200 | 2026-06-03 | Buy |
4-NITROPHENYL TRIFLUOROACETATE Chemical Properties,Uses,Production
Chemical Properties
Beige crystalline
Uses
4-Nitrophenyl Trifluoroacetate is used as a reagent for the preparation of 4-nitrophenyl active esters from acids.
Purification Methods
Recrystallise the ester from CHCl3/hexane [Margolis et al. J Biol Chem 253 7891 1978]. It sublimes in vacuo (m 36-38o). It is moisture sensitive. [Sakakibara & Inukai Bull Chem Soc Jpn 37 1231 1964.]
Precautions
4-Nitrophenyl Trifluoroacetate is water sensitive; should be stored in a tightly closed bottle.
4-NITROPHENYL TRIFLUOROACETATE Preparation Products And Raw materials
Global( 171)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 472 | 75 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Lastest Price from 4-NITROPHENYL TRIFLUOROACETATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 4-NITROPHENYL TRIFLUOROACETATE
658-78-6
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-04-04 | 4-NITROPHENYL TRIFLUOROACETATE
658-78-6
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2021-10-21 | 4-NITROPHENYL TRIFLUOROACETATE
658-78-6
|
$10.00 | 1KG | 99% | 20 tons | Hebei Zhanyao Biotechnology Co. Ltd |
-
- 4-NITROPHENYL TRIFLUOROACETATE
658-78-6
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-NITROPHENYL TRIFLUOROACETATE
658-78-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 4-NITROPHENYL TRIFLUOROACETATE
658-78-6
- $10.00
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
658-78-6(4-NITROPHENYL TRIFLUOROACETATE)Related Search:
trifluoro-aceticaci4-nitrophenylester
4-Nitrophenyl trifluoroacetate 99%
4-Nitrophenyltrifluoroacetate99%
4-NITROPHENYL TRIFLUOROACETATE 97+%
Trifluoro-Ac
Trifluoroacetic acid 4-nitrophenyl ester, 4-Nitrophenyl 2,2,2-tri
(4-nitrophenyl) 2,2,2-trifluoroacetate
(4-nitrophenyl) 2,2,2-trifluoroethanoate
2,2,2-trifluoroacetic acid (4-nitrophenyl) ester
p-Nitrophenyl trifuoroacetate
TFAONP 4-Nitrophenyl Trifluoroacetate
Trifluoroacetic acid 4-nitrophenyl ester, 4-Nitrophenyl 2,2,2-trifluoroethanoate
4-Nitrophenyl trifluoroacetate≥ 99% (HPLC)
P-NITROPHENYL TRIFLUOROACETATE
NITROPHENYLTRIFLUOROACETATE(4-)
SAKAKI BARA'S REAGENT
TRIFLUOROACETIC ACID 4-NITROPHENYL ESTER
Acetic acid, trifluoro-, p-nitrophenyl ester
Trifluoroacetic acid p-nitrophenyl ester
4-NITROPHENYL TRIFLUOROACETATE
TFAONP
4-Nitrophenyl Trifluoroacetate(TFAONP)
4-Nitrophenyl Trifluoroacetate >
Acetic acid, 2,2,2-trifluoro-, 4-nitrophenyl ester
4-NITROPHENYL TRIFLUOROACETATE ISO 9001：2015 REACH
4-Nitrophenyltrifluoracetat
658-78-6
C8H4F3NO4
CF3CO2C6H4NO2
Condensation & Active Esterification
Synthetic Reagents
Coupling
Active Esters/Additives
Condensation & Active Esterification
Synthetic Organic Chemistry
Active Esters/Additives
Active Esters/AdditivesSynthetic Reagents
Coupling
Peptide Synthesis
