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7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione

7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione structure

CAS No.: 168123-82-8

Chemical Name:: 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione

Synonyms: 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione;7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione;7-broMo-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-2,3-dione;7-Bromo-2,3-dioxo-1,4-dihydro-pyrido[2,3-b]pyrazine;Pyrido[2,3-b]pyrazine-2,3-dione, 7-bromo-1,4-dihydro-;7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE ISO 9001：2015 REACH

CBNumber:: CB0335319

Molecular Formula:: C7H4BrN3O2

Molecular Weight:: 242.03

MDL Number:: MFCD08236693

MOL File:: 168123-82-8.mol

MSDS File:: SDS

Last updated:2026-09-12 18:48:18

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7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione Properties

Density	1.851±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	7.95±0.20(Predicted)
Appearance	Brown to gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	072303	7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione	168123-82-8	250.00mg	$416	2026-05-18	Buy
Matrix Scientific	072303	7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione	168123-82-8	1.00g	$899	2026-05-18	Buy
Matrix Scientific	072303	7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione	168123-82-8	5.00g	$2233	2026-05-18	Buy
aablocks	AA001XR7	7-Bromopyrido[2,3-B]Pyrazine-2,3(1H,4H)-Dione ≥95%	168123-82-8	250mg	$10	2026-05-28	Buy
aablocks	AA001XR7	7-Bromopyrido[2,3-B]Pyrazine-2,3(1H,4H)-Dione ≥95%	168123-82-8	1g	$28	2026-05-28	Buy

Product number	Packaging	Price	Buy
072303	250.00mg	$416	Buy
072303	1.00g	$899	Buy
072303	5.00g	$2233	Buy
AA001XR7	250mg	$10	Buy
AA001XR7	1g	$28	Buy

7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione Chemical Properties, Uses, Production

Synthesis

38875-53-5

95-92-1

168123-82-8

General procedure for the synthesis of 7-bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione from 2,3-diamino-5-bromopyridine and diethyl oxalate: a mixture of 2,3-diamino-5-bromopyridine (1 mmol) and diethyl oxalate (10 mL) was heated and refluxed for 4 hours. After completion of the reaction, it was cooled to room temperature. The resulting solid was collected by filtration and washed sequentially with ethyl acetate and 95% ethanol. Subsequently, the solid was decolorized using activated charcoal and recrystallized in a solvent mixture of water and DMF or DMSO to afford 7-bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione as a white solid (620 mg, 25.6% yield). The product was characterized by IR (KBr) ν 31199, 3138, 3045, 2751, 1715, 1603, 1446, 1389 cm-1; 1H NMR (400 MHz, DMSO-d6) δ 7.55 (1H, d, J = 1.6 Hz, H-6), 8.15 (1H, d, J = 1.6 Hz, H-8); 13C NMR (100 MHz, DMSO-d6) δ 112.36, 123.20, 123.80, 138.46, 141.83, 154.55, 155.58; HRMS-EI C7H4BrN3O2 calculated value [M + H]+ 241.9565, measured value 241.9567.

References

[1] European Journal of Medicinal Chemistry, 2016, vol. 117, p. 19 - 32
[2] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 308 - 317
[3] Journal of Medicinal Chemistry, 2018, vol. 61, # 7, p. 2949 - 2961

7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione Preparation Products And Raw materials

Raw materials

2,3-Diamino-5-bromopyridine Diethyl oxalate

Preparation Products

7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione Suppliers

Global Suppliers ( 63)

Supplier	Tel	Email	Country	ProdList	Advantage
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29977	65
Chengdu Research Accelerators Technology Co., Ltd.	028-64353063	reacchemical@163.com	China	5243	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Aikon International Limited	025-66061636 19370895928	qqyang@aikonchem.com	China	15810	58
Xenoah Pharmaceutical Inc.	0512-6956-1983	info@xenoah.com	China	295	58
SuZhou Medinoah Co.,LTD.	0512-69561983 13914027025	zhang_q@medinoah.com	China	3925	58
Shanghai Jizhi Biochemical Technology Co. Ltd.	021-4009004166/18616739031 18616739031	3007523370@qq.com	China	40000	58
Chongqing Zhisheng Technology Co., Ltd.	023-67586781 17783613370	2636861874@qq.com	China	446	58

Supplier	Advantage
Pure Chemistry Scientific Inc.	62
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
Chengdu Research Accelerators Technology Co., Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Amadis Chemical Company Limited	58
Aikon International Limited	58
Xenoah Pharmaceutical Inc.	58
SuZhou Medinoah Co.,LTD.	58
Shanghai Jizhi Biochemical Technology Co. Ltd.	58
Chongqing Zhisheng Technology Co., Ltd.	58

View Latest Price from 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE 168123-82-8	$1.10	1g	99.00%	100 Tons min	Dideu Industries Group Limited
	2020-05-13	7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione 168123-82-8		1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd

7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE
168123-82-8
$1.10
99.00%
Dideu Industries Group Limited

7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione
168123-82-8
99.0%
Shaanxi Dideu Medichem Co. Ltd

7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione Spectrum

7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE(168123-82-8)¹HNMR

168123-82-8 (7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione) Related Search:

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1of4

7-Bromo-2,3-dioxo-1,4-dihydro-pyrido[2,3-b]pyrazine 7-broMo-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-2,3-dione 7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione Pyrido[2,3-b]pyrazine-2,3-dione, 7-bromo-1,4-dihydro- 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE ISO 9001：2015 REACH 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione 168123-82-8