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Tetramethylammonium acetate

CAS No.
10581-12-1
Chemical Name:
Tetramethylammonium acetate
Synonyms
TETRAMETHYLAMMONIUM ACETATE HYDRATE;[M4N]Ac;tetraMethylazaniuM;Tetramethylazanium acetate;TetraMethylaMMoniuM acetat;TETRAMETHYLAMMONIUM ACETATE;n,n,n-trimethyl-methanaminiuacetate;TETRAMETHYLAMMONIUM ACETATE, 90% TECH.;METHANAMINIUM,N,N,N-TRIMETHYL-,ACETATE;Tetramethylammonium acetate, tech. 90%
CBNumber:
CB0348065
Molecular Formula:
C6H15NO2
Molecular Weight:
133.19
MDL Number:
MFCD00011630
MOL File:
10581-12-1.mol
MSDS File:
SDS
Last updated:2026-05-27 17:40:25
Product description Number Pack Size Price
Tetramethylammonium acetate ≥97% 245070 5g $28.5
Tetramethylammonium acetate ≥97% 245070 25g $136
Tetramethylammonium Acetate >98.0%(T) T1048 5g $46
Tetramethylammonium Acetate >98.0%(T) T1048 25g $153
Tetramethylammonium acetate monohydrate FT37551 100g $265
More product size

Tetramethylammonium acetate Properties

Melting point 184 °C (dec.) (lit.)
Density 1.000g/cm3 at 20°C
storage temp. Store below +30°C.
form Crystalline Solid
color White
Water Solubility Soluble in water.
Sensitive Hygroscopic
BRN 3571830
InChI InChI=1S/C4H12N.C2H4O2/c1-5(2,3)4;1-2(3)4/h1-4H3;1H3,(H,3,4)/q+1;/p-1
InChIKey MRYQZMHVZZSQRT-UHFFFAOYSA-M
SMILES [N+](C)(C)(C)C.C(=O)([O-])C
CAS DataBase Reference 10581-12-1(CAS DataBase Reference)
EPA Substance Registry System Methanaminium, N,N,N-trimethyl-, acetate (10581-12-1)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-37/39
WGK Germany  3
3-10
TSCA  TSCA listed
HS Code  29239000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
NFPA 704
1
2 0

Tetramethylammonium acetate price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 245070 Tetramethylammonium acetate ≥97% 10581-12-1 5g $28.5 2026-04-30 Buy
Sigma-Aldrich 245070 Tetramethylammonium acetate ≥97% 10581-12-1 25g $136 2026-04-30 Buy
TCI Chemical T1048 Tetramethylammonium Acetate >98.0%(T) 10581-12-1 5g $46 2026-04-30 Buy
TCI Chemical T1048 Tetramethylammonium Acetate >98.0%(T) 10581-12-1 25g $153 2026-04-30 Buy
Biosynth FT37551 Tetramethylammonium acetate monohydrate 10581-12-1 100g $265 2026-06-04 Buy
Product number Packaging Price Buy
245070 5g $28.5 Buy
245070 25g $136 Buy
T1048 5g $46 Buy
T1048 25g $153 Buy
FT37551 100g $265 Buy

Tetramethylammonium acetate Chemical Properties,Uses,Production

Chemical Properties

clear colorless to pale yellow solution

Uses

Tetramethylammonium acetate is used as an intermediate in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. Further, it is used to prepare (1R,4S)-4-hydroxycyclopent-2-en-1-essigsaeure-methylester by reacting with 1,3-dimethyl-imidazolidin-2-one. In addition to this, it serves as an emulsifier, catalyst, sterilizer, antistatic and antiseptic agent.

Synthesis

Tetramethylammonium hydroxide

75-59-2

Acetic acid

64-19-7

Tetramethylammonium acetate

10581-12-1

General procedure for the synthesis of tetramethylammonium acetate from tetramethylammonium hydroxide and glacial acetic acid: 247 mg (4.11 mmol) of glacial acetic acid and 1.50 g (4.11 mmol) of tetramethylammonium hydroxide (25% wt. of methanol solution) were dissolved in 10 mL of methanol. The reaction mixture was stirred at 40°C for 4 hours. Upon completion of the reaction, the reaction solution was filtered and the solvent was subsequently removed using a rotary evaporator to give a viscous oil which gradually solidified. The residual trace solvent was removed under high vacuum to give a white solid product. The white solid was washed with ether and subsequently dried under vacuum to give 480 mg of white solid tetramethylammonium acetate in 87.6% yield.

References

[1] Patent: US2010/105770, 2010, A1. Location in patent: Page/Page column 12

75-59-2
64-19-7
10581-12-1
Synthesis of Tetramethylammonium acetate from Tetramethylammonium hydroxide and Acetic acid
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View Lastest Price from Tetramethylammonium acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tetramethylammonium acetate pictures 2026-09-09 Tetramethylammonium acetate
10581-12-1
1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Tetramethylammonium acetate pictures 2026-09-02 Tetramethylammonium acetate
10581-12-1
$5.00 1KG 99% Henan Fengda Chemical Co., Ltd
Tetramethylammonium acetate pictures 2026-03-20 Tetramethylammonium acetate
10581-12-1
$9.90 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
TETRAMETHYLAMMONIUM ACETATE n,n,n-trimethyl-methanaminiuacetate TETRAMETHYLAMMONIUM ACETATE, 90% TECH. Tetramethylammonium acetate, 50% aqueous solution METHANAMINIUM,N,N,N-TRIMETHYL-,ACETATE Tetramethylammonium Acetate (ca. 15% in Water) Tetramethylammonium acetate, tech. 90% TetraMethylaMMoniuM acetate Monohydrate Tetramethylazanium acetate tetraMethylazaniuM TetraMethylaMMoniuM acetate, 50% aqueous solution 5GR TetraMethylaMMoniuM acetat Tetramethylammonium acetate technical grade, 90% [M4N]Ac TetraMethylaMMoniuM Acetate , 98.0%(T) Methanaminium, N,N,N-trimethyl-, acetate (1:1) Tetramethylammonium acetate ISO 9001:2015 REACH CAS10581-12-1 Tetramethylammonium acetate TETRAMETHYLAMMONIUM ACETATE HYDRATE 10581-12-1 C4H12NC2H3O2 C6H15NO2xH2O CH34NOCOCH3 CH34NOOCCH3 CH34NOAc CH34NOCOCH3xH2O C2H3O2C4H12N C4H12NC2H3O2H2O Phase Transfer Catalysts Synthetic Reagents Ammonium Salts Ammonium Polyhalides, etc. (Quaternary) Quaternary Ammonium Compounds quarternary ammonium salts Ammonium Polyhalides, etc. (Quaternary) Quaternary Ammonium Compounds Ammonium Salts Greener Alternatives: Catalysis Phase Transfer Catalysts bc0001