N-Formylglycine
- CAS No.
- 2491-15-8
- Chemical Name:
- N-Formylglycine
- Synonyms
- FOR-GLY-OH;N-For-Gly-OH;Formylglycin;N-FORMYLGLYCIN;FORMYL-GLYCINE;N-FORMYLGLYCINE;N-α-Formylglycine;N-Formylglycine>Glycine, N-formyl-;N-FORMYLGLYCINE 98+%
- CBNumber:
- CB0359737
- Molecular Formula:
- C3H5NO3
- Molecular Weight:
- 103.08
- MDL Number:
- MFCD00037360
- MOL File:
- 2491-15-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 149-151 °C |
|---|---|
| Boiling point | 193.26°C (rough estimate) |
| Density | 1.4873 (rough estimate) |
| refractive index | 1.4940 (estimate) |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | pK1:3.43 (25°C) |
| color | White |
| Water Solubility | very faint turbidity |
| BRN | 1749108 |
| Major Application | peptide synthesis |
| InChI | 1S/C3H5NO3/c5-2-4-1-3(6)7/h2H,1H2,(H,4,5)(H,6,7) |
| InChIKey | UGJBHEZMOKVTIM-UHFFFAOYSA-N |
| SMILES | OC(=O)CNC=O |
| CAS DataBase Reference | 2491-15-8(CAS DataBase Reference) |
| FDA UNII | 11F24CG16M |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MC0547000 | |||||||||
| HS Code | 29241990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Toxicity | LD50 unreported in rat: > 3gm/kg | |||||||||
| NFPA 704 |
|
N-Formylglycine price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 47723 | N-Formylglycine ≥98.0% | 2491-15-8 | 5g | $369 | 2023-06-20 | Buy |
| TCI Chemical | F0121 | N-Formylglycine >98.0%(T) | 2491-15-8 | 5g | $86 | 2026-04-30 | Buy |
| TCI Chemical | F0121 | N-Formylglycine >98.0%(T) | 2491-15-8 | 25g | $273 | 2026-04-30 | Buy |
| TRC | TRC-F700445-5G | N-Formylglycine | 2491-15-8 | 5g | $129 | 2026-06-03 | Buy |
| TRC | TRC-F700445-2.5G | N-Formylglycine | 2491-15-8 | 2.5g | $91 | 2026-06-03 | Buy |
N-Formylglycine Chemical Properties, Uses, Production
Chemical Properties
White solid
Uses
N-Formylglycine is a simple dipeptide and a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.
Definition
ChEBI: An N-acylglycine resulting from the formal condensation of the amino group of glycine with formic acid.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
64-18-6
56-40-6
2491-15-8
The general procedure for the synthesis of 2-formamidoacetic acid from formic acid and glycine was as follows: formic acid (140 mL, 3.71 mol) was reacted with acetic anhydride (47 mL, 0.50 mol) with stirring for 1 hour at 45 °C. Subsequently, glycine (0.05 mol) was added to the reaction mixture and stirring was continued at room temperature for 24 hours. After completion of the reaction, the mixture was evaporated to dryness to afford the target product 2-formamidoacetic acid.
References
[1] Organic and Biomolecular Chemistry, 2015, vol. 14, # 1, p. 93 - 96
[2] Synthetic Communications, 1983, vol. 13, # 9, p. 745 - 752
[3] Organic Letters, 2018, vol. 20, # 18, p. 5877 - 5880
[4] Chemical Communications, 2012, vol. 48, # 31, p. 3775 - 3777
[5] Tetrahedron, 2013, vol. 69, # 43, p. 9161 - 9165
N-Formylglycine Preparation Products And Raw materials
Raw materials
Preparation Products
N-Formylglycine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from N-Formylglycine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | N-Formylglycine
2491-15-8
|
$29.00 | 99.79% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-08-12 | N-Formylglycine
2491-15-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-09-02 | N-Formylglycine
2491-15-8
|
$1.00 | 1KG | ≥98% | 200KG | Career Henan Chemical Co |
-
- N-Formylglycine
2491-15-8
- $29.00
- 99.79%
- TargetMol Chemicals Inc.
-
- N-Formylglycine
2491-15-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- N-Formylglycine
2491-15-8
- $1.00
- ≥98%
- Career Henan Chemical Co
