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2'-Trifluoromethyl-biphenyl-4-carbaldehyde

CAS No.
198205-95-7
Chemical Name:
2'-Trifluoromethyl-biphenyl-4-carbaldehyde
Synonyms
AKOS BAR-1774;4-[2-(TRIFLUOROMETHYL)PHENYL]BENZALDEHYDE;2'-trifluoromethyl diphenyl-4-carbaldehyde;2'-Trifluoromethyl-biphenyl-4-carbaldehyde;2'-(TRIFLUOROMETHYL)[1,1'-BIPHENYL]-4-CARBALDEHYDE;2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carbaldehyde;2'-(Trifluoromethyl)[1,1'-biphenyl]-4-carboxaldehyde;[1,1'-Biphenyl]-4-carboxaldehyde, 2'-(trifluoromethyl)-;2′-Trifluoromethyl-biphenyl-4-carbaldehyde, CAS 198205-95-7
CBNumber:
CB0381341
Molecular Formula:
C14H9F3O
Molecular Weight:
250.22
MDL Number:
MFCD01631916
MOL File:
198205-95-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:19

2'-Trifluoromethyl-biphenyl-4-carbaldehyde Properties

Boiling point 338.8±42.0 °C(Predicted)
Density 1.251±0.06 g/cm3(Predicted)
CAS DataBase Reference 198205-95-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36

2'-Trifluoromethyl-biphenyl-4-carbaldehyde price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech AR2075 4-[2-(TRIFLUOROMETHYL)PHENYL]BENZALDEHYDE 95% 198205-95-7 1G $34 2026-04-30 Buy
AstaTech AR2075 4-[2-(TRIFLUOROMETHYL)PHENYL]BENZALDEHYDE 95% 198205-95-7 5G $107 2026-04-30 Buy
AstaTech AR2075 4-[2-(TRIFLUOROMETHYL)PHENYL]BENZALDEHYDE 95% 198205-95-7 25G $477 2026-04-30 Buy
Activate Scientific AS30288 2`-Trifluoromethyl-biphenyl-4-carbaldehyde 98% 198205-95-7 1g $73 2026-06-04 Buy
Activate Scientific AS30288 2`-Trifluoromethyl-biphenyl-4-carbaldehyde 98% 198205-95-7 5g $227 2026-06-04 Buy
Product number Packaging Price Buy
AR2075 1G $34 Buy
AR2075 5G $107 Buy
AR2075 25G $477 Buy
AS30288 1g $73 Buy
AS30288 5g $227 Buy

2'-Trifluoromethyl-biphenyl-4-carbaldehyde Chemical Properties, Uses, Production

Synthesis

2-Bromobenzotrifluoride

392-83-6

4-Formylphenylboronic acid

87199-17-5

2'-TRIFLUOROMETHYL-BIPHENYL-4-CARBALDEHYDE

198205-95-7

A solution of tetrakis(triphenylphosphine)palladium (0.05 g) and sodium carbonate (0.7 g) in water (5 mL) was sequentially added to a stirred solution of o-bromobenzotrifluorotoluene (0.7 g, 2.75 mmol) and 4-formylbenzeneboronic acid (0.5 g, 3.3 mmol) in dioxane (20 mL) under nitrogen protection and at 80 °C. The reaction mixture was stirred at 100±5°C for 6 hours. Upon completion of the reaction, the solvent was removed by evaporation and the residue was diluted to 50 mL with ethyl acetate and washed with deionized water. The solvent was again removed by evaporation and the residue was purified by silica gel column chromatography (FCC) to afford 2'-(trifluoromethyl)-[1,1'-biphenyl]-4-carbaldehyde (0.61 g, 88% yield) as a milky white solid.1H-NMR (CDCl3) δ: 7.49 (d, 1H, J = 7.41 Hz); 7.48 (d, 2H, J = 8.13 Hz); 7.61-7.53 (m, 2H); 7.76 (d, 1H, J = 7.8 Hz); 7.91 (d, 2H, J = 8.34 Hz); 10.07 (s, 1H).

References

[1] Patent: WO2010/42998, 2010, A1. Location in patent: Page/Page column 95

2'-Trifluoromethyl-biphenyl-4-carbaldehyde Preparation Products And Raw materials

Global Suppliers ( 73)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Shanghai Meishui Chemical Technology Co., Ltd 021-60549325 18616193163 China 4518 56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Chengdu Research Accelerators Technology Co., Ltd. 028-64353063 reacchemical@163.com China 5243 58

View Latest Price from 2'-Trifluoromethyl-biphenyl-4-carbaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2 2021-08-12 2"-TRIFLUOROMETHYL-BIPHENYL-4-CARBALDEHYDE
198205-95-7
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
4-[2-(TRIFLUOROMETHYL)PHENYL]BENZALDEHYDE AKOS BAR-1774 2'-(TRIFLUOROMETHYL)[1,1'-BIPHENYL]-4-CARBALDEHYDE [1,1'-Biphenyl]-4-carboxaldehyde, 2'-(trifluoromethyl)- 2'-(Trifluoromethyl)[1,1'-biphenyl]-4-carboxaldehyde 2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carbaldehyde 2'-Trifluoromethyl-biphenyl-4-carbaldehyde 2′-Trifluoromethyl-biphenyl-4-carbaldehyde, CAS 198205-95-7 2'-trifluoromethyl diphenyl-4-carbaldehyde 198205-95-7 ALDEHYDE Biphenyl & Diphenyl ether